Factsheet for PGSC0003DMT400070070

Subcellular Localization

min:

: max

Winner_takes_all: peroxisome, nucleus, cytosol

Predictor Summary:

nucleus 2
extracellular 1
peroxisome 2
mitochondrion 1
cytosol 1

Predictors

GFP

MS/MS

Papers

PPI

No PPI Data

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
GSMUA_Achr2P17790_001	Banana	cytosol	25.0	76.88
CDX72028	Canola	cytosol	58.22	59.78
PGSC0003DMT400070079	Potato	cytosol	22.03	57.27
Solyc04g015680.2.1	Tomato	cytosol, extracellular	97.03	57.16
VIT_08s0007g08490.t01	Wine grape	cytosol	75.35	44.66
VIT_08s0007g08480.t01	Wine grape	cytosol	74.13	43.94
AT2G41790.1	Thale cress	cytosol	69.23	40.82
Bra004649.1-P	Field mustard	cytosol	68.36	40.31
CDX79914	Canola	cytosol	68.18	40.21
AT3G57470.2	Thale cress	cytosol	67.66	40.06
CDY48762	Canola	cytosol	67.83	40.0
Bra007329.1-P	Field mustard	cytosol	66.61	39.65
KXG36518	Sorghum	cytosol	68.36	39.34
Os07t0570300-01	Rice	plastid	67.83	39.27
CDY06103	Canola	cytosol	66.96	39.2
TraesCS2D01G206200.1	Wheat	cytosol, golgi, unclear	67.48	39.11
TraesCS2B01G225800.2	Wheat	cytosol	67.48	39.11
Zm00001d021846_P016	Maize	cytosol	68.01	39.06
TraesCS2A01G198400.1	Wheat	cytosol, golgi	66.96	38.8
CDX88949	Canola	cytosol	65.21	38.3
CDY31008	Canola	cytosol	65.03	38.19
Bra014622.1-P	Field mustard	cytosol	64.51	37.88
Os07t0570500-01	Rice	cytosol, plasma membrane	64.69	37.53
HORVU2Hr1G038720.19	Barley	extracellular	60.66	37.39
Os07t0570100-01	Rice	cytosol, plasma membrane	64.16	37.0
TraesCS3D01G312900.2	Wheat	cytosol	62.06	36.75
TraesCS3B01G347600.1	Wheat	cytosol	61.89	36.61
TraesCS3A01G318300.2	Wheat	cytosol	61.89	36.61
CDY61872	Canola	cytosol	63.29	36.6
EES01562	Sorghum	cytosol	62.41	36.5
Os01t0778800-01	Rice	plasma membrane	61.54	36.18
HORVU3Hr1G076480.7	Barley	cytosol	60.49	35.82
Zm00001d012628_P001	Maize	cytosol	11.89	35.42
Zm00001d043274_P008	Maize	plastid	60.14	34.99
CDY33819	Canola	cytosol, extracellular	55.94	32.96
Os01t0779100-00	Rice	plasma membrane	49.48	32.91
GSMUA_Achr2P17800_001	Banana	cytosol	41.96	31.66
AT3G57460.1	Thale cress	cytosol, extracellular	11.19	25.1
CDY54849	Canola	cytosol	4.37	14.62
CDY43076	Canola	cytosol	10.84	8.65
CDY33824	Canola	extracellular	0.7	3.05
Zm00001d012627_P001	Maize	cytosol	0.7	1.57
PGSC0003DMT400070080	Potato	peroxisome	0.87	1.4
CDY72352	Canola	cytosol, peroxisome	0.17	0.3

Protein Annotations

MapMan:19.4.5.4.2	Gene3D:3.30.830.10	GO:GO:0003674	GO:GO:0003824	GO:GO:0004222	GO:GO:0005488
GO:GO:0006508	GO:GO:0008150	GO:GO:0008152	GO:GO:0016787	GO:GO:0019538	GO:GO:0046872
MEROPS:M16.017	UniProt:M1CLN2	InterPro:Metalloenz_LuxS/M16	PFAM:PF00675	PFAM:PF05193	PFAM:PF16187
EnsemblPlantsGene:PGSC0003DMG400027247	PGSC:PGSC0003DMG400027247	EnsemblPlants:PGSC0003DMT400070070	ScanProsite:PS00143	PANTHER:PTHR43690	PANTHER:PTHR43690:SF7
InterPro:Pept_M16_N	InterPro:Pept_M16_Zn_BS	InterPro:Peptidase_M16_C	InterPro:Peptidase_M16_M	SUPFAM:SSF63411	UniParc:UPI000294EC9F

Description

Insulin degrading enzyme [Source:PGSC_GENE;Acc:PGSC0003DMG400027247]

Coordinates

chr4:+:10057649..10074774

Molecular Weight (calculated)

65681.8 Da

IEP (calculated)

5.663

GRAVY (calculated)

-0.430

Length

572 amino acids

Sequence
(BLAST)

001: MAVGKKEENM AVEIVKPRID KRDYRRIVLQ NNLEILLISD PETDKCAASM NVCVGAFSDP EGLEGLAHFL EHMLFYASEK YPVEDSYSKY ITENGGSTNA
101: FTSSEDTNYY FEVNADGFEE ALDRFAQFFI KPLMSADATT REIKAVDSEH QKNLLSDPWR MNQLQKHLSA ENHPYHKFST GSWDTLEVRP KERGIDTRQE
201: LLKFYSENYS ANLMHLVVYS KDSLDKVEQL VRGKFQDIRN IDRNQIHFTG QPCTTEHLQI LVRAVPIKQG HKLKIIWPIT PGIHHYKEGP CRYLGHLIGH
301: EGEGSLFYVL KKLGWATSLS AGESDWTNEF SFFKVAIDLT DAGQDHFEDI MGLLFKYIHL LQQAGASKWI FEELSAICET AFHYQDKIRP SDYVVNVAMN
401: MQHYPPEDWL VASSLPSKFN PSVIQSFLNE LNPDNVRIFW ESTKFEGNTS MTEPWYGTAY SMEKVGGDSI KHWMEHAPSE ELHLPAPNVF IPTDLSLKPV
501: FEKTKVPILL RKSPYSRLWY KPDTAFSSPK AYVMIDFSCP YGGHSPEAEV LTEIFTRLLM DYLNEYGTSA RY

Best Arabidopsis Sequence Match ( AT2G41790.1 )
(BLAST)

001: MAVEKSNTTV GGVEILKPRT DNREYRMIVL KNLLQVLLIS DPDTDKCAAS MSVSVGSFSD PQGLEGLAHF LEHMLFYASE KYPEEDSYSK YITEHGGSTN
101: AYTASEETNY HFDVNADCFD EALDRFAQFF IKPLMSADAT MREIKAVDSE NQKNLLSDGW RIRQLQKHLS KEDHPYHKFS TGNMDTLHVR PQAKGVDTRS
201: ELIKFYEEHY SANIMHLVVY GKESLDKIQD LVERMFQEIQ NTNKVVPRFP GQPCTADHLQ ILVKAIPIKQ GHKLGVSWPV TPSIHHYDEA PSQYLGHLIG
301: HEGEGSLFHA LKTLGWATGL SAGEGEWTLD YSFFKVSIDL TDAGHEHMQE ILGLLFNYIQ LLQQTGVCQW IFDELSAICE TKFHYQDKIP PMSYIVDIAS
401: NMQIYPTKDW LVGSSLPTKF NPAIVQKVVD ELSPSNFRIF WESQKFEGQT DKAEPWYNTA YSLEKITSST IQEWVQSAPD VHLHLPAPNV FIPTDLSLKD
501: ADDKETVPVL LRKTPFSRLW YKPDTMFSKP KAYVKMDFNC PLAVSSPDAA VLTDIFTRLL MDYLNEYAYY AQVAGLYYGV SLSDNGFELT LLGYNHKLRI
601: LLETVVGKIA NFEVKPDRFA VIKETVTKEY QNYKFRQPYH QAMYYCSLIL QDQTWPWTEE LDVLSHLEAE DVAKFVPMLL SRTFIECYIA GNVENNEAES
701: MVKHIEDVLF NDPKPICRPL FPSQHLTNRV VKLGEGMKYF YHQDGSNPSD ENSALVHYIQ VHRDDFSMNI KLQLFGLVAK QATFHQLRTV EQLGYITALA
801: QRNDSGIYGV QFIIQSSVKG PGHIDSRVES LLKNFESKLY EMSNEDFKSN VTALIDMKLE KHKNLKEESR FYWREIQSGT LKFNRKEAEV SALKQLQKQE
901: LIDFFDEYIK VGAARKKSLS IRVYGSQHLK EMASDKDEVP SPSVEIEDIV GFRKSQPLHG SFRGCGQPKL

Arabidopsis Description

PXM16Insulin-degrading enzyme-like 1, peroxisomal [Source:UniProtKB/Swiss-Prot;Acc:O22941]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.