Subcellular Localization
min:
: max
Winner_takes_all: cytosol
Predictor Summary:
Predictor Summary:
- nucleus 2
- cytosol 2
- mitochondrion 1
Predictors | GFP | MS/MS | Papers | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PPI
No PPI Data
Homology
Paralog
locus | Identity | Homology Identity |
---|
Ortholog
locus | Homology Species | Location | Identity | Homology Identity |
---|---|---|---|---|
CDY27054 | Canola | cytosol | 63.1 | 63.54 |
CDX70232 | Canola | cytosol, plastid | 77.93 | 60.11 |
CDY58433 | Canola | cytosol | 63.79 | 58.73 |
CDY47999 | Canola | cytosol | 79.66 | 58.63 |
CDY44851 | Canola | cytosol | 55.52 | 58.33 |
CDY51318 | Canola | plastid | 76.21 | 56.96 |
CDX70231 | Canola | cytosol | 75.17 | 55.61 |
CDY44849 | Canola | cytosol | 74.48 | 55.1 |
CDY19749 | Canola | cytosol | 73.79 | 54.59 |
CDX87021 | Canola | cytosol | 73.1 | 54.08 |
CDY65325 | Canola | cytosol | 63.79 | 52.71 |
CDX70229 | Canola | cytosol | 71.38 | 52.67 |
CDY23695 | Canola | endoplasmic reticulum | 41.03 | 52.65 |
CDX70230 | Canola | cytosol, plastid | 70.34 | 51.78 |
CDX73874 | Canola | cytosol | 64.48 | 48.83 |
CDY01022 | Canola | cytosol | 48.62 | 48.45 |
CDY01018 | Canola | endoplasmic reticulum | 40.0 | 48.33 |
CDY69068 | Canola | cytosol | 64.48 | 47.95 |
CDY67082 | Canola | cytosol, plastid | 42.76 | 46.44 |
CDY08520 | Canola | cytosol | 60.69 | 45.95 |
CDY08522 | Canola | cytosol | 43.45 | 45.82 |
CDX83129 | Canola | cytosol | 50.69 | 40.5 |
CDX77965 | Canola | cytosol | 33.79 | 38.13 |
CDY11287 | Canola | cytosol | 63.79 | 37.53 |
CDY54689 | Canola | cytosol | 41.03 | 36.84 |
Solyc01g080970.2.1 | Tomato | cytosol | 38.97 | 35.09 |
CDX73768 | Canola | cytosol | 48.62 | 34.39 |
Solyc01g080990.2.1 | Tomato | cytosol | 40.69 | 33.24 |
PGSC0003DMT400004581 | Potato | cytosol | 41.03 | 32.51 |
Solyc10g061840.1.1 | Tomato | cytosol | 39.66 | 32.49 |
VIT_04s0023g02200.t01 | Wine grape | cytosol | 38.62 | 31.28 |
GSMUA_Achr7P20400_001 | Banana | cytosol | 21.72 | 31.19 |
PGSC0003DMT400004564 | Potato | cytosol, mitochondrion, nucleus | 24.48 | 31.14 |
Zm00001d015216_P001 | Maize | cytosol | 26.55 | 29.96 |
KRH65522 | Soybean | cytosol | 38.62 | 29.87 |
KRH62438 | Soybean | cytosol, mitochondrion, peroxisome | 26.55 | 29.84 |
Zm00001d015224_P001 | Maize | cytosol, endoplasmic reticulum | 28.28 | 29.29 |
HORVU7Hr1G040170.1 | Barley | cytosol | 35.52 | 28.93 |
CDY51317 | Canola | mitochondrion | 78.28 | 28.88 |
Os06t0242000-01 | Rice | cytosol | 35.17 | 28.73 |
Os06t0315000-00 | Rice | cytosol | 32.41 | 28.66 |
CDY24788 | Canola | cytosol | 35.86 | 28.65 |
CDX69227 | Canola | cytosol | 36.55 | 28.65 |
CDX75578 | Canola | cytosol | 36.55 | 28.65 |
TraesCSU01G190500.1 | Wheat | cytosol | 29.31 | 28.24 |
TraesCSU01G190800.1 | Wheat | cytosol | 29.31 | 28.24 |
TraesCSU01G219100.1 | Wheat | cytosol | 29.31 | 28.24 |
TraesCSU01G230800.1 | Wheat | cytosol | 29.31 | 28.24 |
Os06t0313440-00 | Rice | cytosol | 19.31 | 28.14 |
CDX96654 | Canola | cytosol | 36.55 | 28.12 |
CDY64928 | Canola | cytosol | 25.86 | 28.09 |
TraesCS3B01G513400.1 | Wheat | peroxisome | 31.72 | 28.05 |
Zm00001d044762_P001 | Maize | cytosol | 36.9 | 28.01 |
CDY44490 | Canola | cytosol | 36.55 | 27.97 |
KRH40363 | Soybean | cytosol | 34.83 | 27.9 |
CDX83754 | Canola | cytosol | 36.55 | 27.82 |
Zm00001d044765_P001 | Maize | cytosol | 36.9 | 27.65 |
HORVU1Hr1G064400.1 | Barley | cytosol | 35.52 | 27.61 |
TraesCSU01G187700.1 | Wheat | peroxisome | 28.97 | 27.54 |
CDY01397 | Canola | cytosol | 37.24 | 27.48 |
Os06t0241400-01 | Rice | cytosol | 35.52 | 27.47 |
Zm00001d044763_P001 | Maize | cytosol | 35.86 | 27.44 |
CDY71401 | Canola | cytosol | 25.17 | 27.34 |
TraesCS7B01G190700.1 | Wheat | cytosol | 34.83 | 27.3 |
CDX83745 | Canola | cytosol | 36.9 | 27.3 |
CDY39364 | Canola | cytosol | 36.9 | 27.3 |
GSMUA_Achr7P20290_001 | Banana | cytosol | 35.17 | 27.27 |
Os06t0314600-01 | Rice | cytosol | 31.72 | 27.22 |
HORVU0Hr1G020630.1 | Barley | cytosol | 34.48 | 27.03 |
Os11t0257700-00 | Rice | cytosol | 21.38 | 26.96 |
TraesCSU01G177400.1 | Wheat | cytosol | 28.28 | 26.89 |
TraesCSU01G225900.1 | Wheat | cytosol | 28.28 | 26.89 |
TraesCS6B01G378100.1 | Wheat | cytosol, nucleus, peroxisome | 34.48 | 26.88 |
TraesCSU01G201200.1 | Wheat | cytosol | 32.07 | 26.88 |
KRH40370 | Soybean | cytosol | 34.14 | 26.83 |
GSMUA_Achr10P... | Banana | cytosol | 34.48 | 26.81 |
CDY29416 | Canola | nucleus | 36.21 | 26.79 |
KRH00866 | Soybean | cytosol | 34.48 | 26.74 |
KRH60813 | Soybean | cytosol, plastid | 33.79 | 26.7 |
CDY53070 | Canola | cytosol | 31.38 | 26.69 |
HORVU3Hr1G023150.1 | Barley | cytosol | 34.14 | 26.68 |
TraesCS7A01G196900.1 | Wheat | cytosol | 34.14 | 26.68 |
TraesCS3B01G445000.1 | Wheat | cytosol | 33.1 | 26.67 |
KRH40367 | Soybean | cytosol | 29.66 | 26.63 |
OQU76154 | Sorghum | cytosol | 37.93 | 26.51 |
TraesCS7A01G223900.1 | Wheat | cytosol | 33.79 | 26.49 |
GSMUA_Achr7P20280_001 | Banana | cytosol | 34.14 | 26.47 |
TraesCS7D01G198200.1 | Wheat | cytosol | 33.79 | 26.42 |
TraesCS3A01G411600.1 | Wheat | cytosol | 32.76 | 26.39 |
Os06t0311800-00 | Rice | cytosol | 31.72 | 26.36 |
GSMUA_AchrUn_... | Banana | cytosol | 34.14 | 26.33 |
TraesCS3A01G412100.1 | Wheat | cytosol | 33.45 | 26.29 |
GSMUA_Achr7P20410_001 | Banana | cytosol | 33.79 | 26.27 |
TraesCS7B01G102600.1 | Wheat | cytosol | 33.45 | 26.15 |
TraesCSU01G212600.1 | Wheat | cytosol | 24.14 | 26.12 |
TraesCS6D01G327800.1 | Wheat | cytosol, nucleus, peroxisome | 33.45 | 26.08 |
GSMUA_Achr7P20420_001 | Banana | cytosol | 33.1 | 26.02 |
GSMUA_Achr7P20380_001 | Banana | cytosol | 33.1 | 25.88 |
TraesCS7A01G042400.1 | Wheat | cytosol | 33.1 | 25.88 |
TraesCS7D01G225800.1 | Wheat | cytosol | 33.1 | 25.88 |
TraesCS3D01G406300.1 | Wheat | peroxisome | 21.38 | 25.83 |
KRH00870 | Soybean | cytosol, mitochondrion, nucleus, plastid | 33.79 | 25.79 |
TraesCS3A01G412200.1 | Wheat | cytosol | 11.38 | 25.78 |
KRH00865 | Soybean | cytosol | 32.76 | 25.75 |
KXG36222 | Sorghum | cytosol | 32.76 | 25.68 |
TraesCS3A01G387400.1 | Wheat | peroxisome | 19.66 | 25.68 |
HORVU2Hr1G026190.2 | Barley | cytosol | 33.1 | 25.67 |
TraesCS1B01G431600.1 | Wheat | cytosol | 33.1 | 25.67 |
TraesCS7A01G224000.1 | Wheat | cytosol | 32.07 | 25.62 |
TraesCS7A01G224200.1 | Wheat | cytosol | 32.76 | 25.61 |
TraesCS7D01G037800.1 | Wheat | cytosol | 32.76 | 25.61 |
TraesCS3D01G466900.1 | Wheat | peroxisome | 31.72 | 25.56 |
Os02t0719600-01 | Rice | cytosol | 33.45 | 25.53 |
Os11t0259700-01 | Rice | cytosol | 34.14 | 25.52 |
TraesCS3B01G065800.1 | Wheat | peroxisome | 30.69 | 25.5 |
TraesCS4A01G445900.1 | Wheat | cytosol | 32.41 | 25.41 |
TraesCS1D01G410300.1 | Wheat | cytosol | 32.76 | 25.4 |
CDY24787 | Canola | cytosol | 27.59 | 25.4 |
TraesCS5A01G197400.1 | Wheat | cytosol | 30.0 | 25.36 |
TraesCS3B01G513900.1 | Wheat | cytosol, endoplasmic reticulum | 13.1 | 25.33 |
TraesCS3B01G514100.1 | Wheat | cytosol, endoplasmic reticulum | 13.1 | 25.33 |
TraesCS3B01G514200.1 | Wheat | cytosol, endoplasmic reticulum | 13.1 | 25.33 |
TraesCSU01G175500.2 | Wheat | peroxisome | 31.38 | 25.28 |
KXG19696 | Sorghum | cytosol | 33.45 | 25.26 |
TraesCS7D01G225600.1 | Wheat | cytosol | 29.31 | 25.22 |
TraesCS3B01G065700.1 | Wheat | peroxisome | 30.34 | 25.21 |
HORVU7Hr1G046820.11 | Barley | cytosol | 29.66 | 25.15 |
EER88049 | Sorghum | cytosol | 31.03 | 25.14 |
GSMUA_Achr7P20390_001 | Banana | cytosol | 22.07 | 25.1 |
Os06t0313320-00 | Rice | peroxisome, vacuole | 31.03 | 25.07 |
TraesCS5D01G560200.1 | Wheat | cytosol | 31.03 | 25.07 |
HORVU7Hr1G007840.2 | Barley | cytosol | 32.07 | 25.07 |
TraesCS7D01G225700.1 | Wheat | cytosol | 32.07 | 25.07 |
TraesCS3D01G464300.1 | Wheat | cytosol, endoplasmic reticulum, peroxisome | 31.03 | 25.0 |
TraesCSU01G170100.1 | Wheat | peroxisome | 30.34 | 25.0 |
TraesCS2A01G024500.1 | Wheat | cytosol | 32.41 | 24.93 |
TraesCS2B01G036300.1 | Wheat | cytosol | 32.41 | 24.93 |
HORVU3Hr1G100270.1 | Barley | cytosol, peroxisome, plastid | 31.03 | 24.93 |
TraesCSU01G201100.1 | Wheat | cytosol | 32.07 | 24.87 |
TraesCSU01G208800.1 | Wheat | cytosol | 32.07 | 24.87 |
CDY14232 | Canola | cytosol | 27.24 | 24.84 |
Os06t0315300-00 | Rice | cytosol | 30.69 | 24.79 |
TraesCS5B01G186200.3 | Wheat | cytosol | 28.97 | 24.78 |
HORVU7Hr1G007620.1 | Barley | cytosol | 32.07 | 24.67 |
KXG29440 | Sorghum | cytosol | 31.38 | 24.66 |
TraesCS3B01G514300.1 | Wheat | cytosol | 30.69 | 24.65 |
TraesCS3D01G406400.1 | Wheat | cytosol | 16.9 | 24.62 |
TraesCS4B01G381300.1 | Wheat | cytosol | 30.69 | 24.59 |
Os11t0256600-00 | Rice | cytosol | 32.76 | 24.55 |
TraesCS7A01G224100.1 | Wheat | cytosol | 31.38 | 24.53 |
KXG29438 | Sorghum | cytosol | 30.69 | 24.52 |
TraesCS2B01G172500.1 | Wheat | cytosol | 31.72 | 24.47 |
TraesCS3B01G513100.1 | Wheat | peroxisome | 30.34 | 24.44 |
TraesCS7D01G229500.1 | Wheat | cytosol | 30.34 | 24.44 |
TraesCS3B01G445100.1 | Wheat | cytosol | 30.0 | 24.44 |
TraesCS6A01G345300.1 | Wheat | cytosol | 28.28 | 24.4 |
GSMUA_Achr7P20300_001 | Banana | cytosol | 35.52 | 24.35 |
TraesCS3A01G468600.1 | Wheat | cytosol | 28.28 | 24.33 |
TraesCS1A01G030400.1 | Wheat | peroxisome | 30.0 | 24.3 |
Zm00001d015217_P001 | Maize | cytosol | 32.76 | 24.23 |
HORVU3Hr1G100190.1 | Barley | cytosol | 30.0 | 24.23 |
TraesCS3A01G471100.1 | Wheat | cytosol | 30.0 | 24.23 |
Zm00001d052829_P001 | Maize | cytosol | 31.38 | 24.2 |
TraesCS3A01G470600.1 | Wheat | peroxisome | 30.0 | 24.17 |
TraesCS3B01G513200.1 | Wheat | peroxisome | 30.0 | 24.17 |
TraesCS7B01G194700.1 | Wheat | cytosol | 30.0 | 24.17 |
TraesCS2B01G034900.1 | Wheat | cytosol | 31.38 | 24.14 |
TraesCS3D01G382000.1 | Wheat | cytosol | 30.0 | 24.1 |
TraesCS3A01G470700.1 | Wheat | peroxisome | 29.31 | 24.08 |
TraesCS3D01G466300.1 | Wheat | peroxisome | 29.31 | 24.08 |
CDY39365 | Canola | endoplasmic reticulum, golgi | 26.9 | 24.07 |
TraesCS2D01G151600.1 | Wheat | cytosol | 31.03 | 24.06 |
Os06t0244000-01 | Rice | golgi | 33.1 | 24.06 |
Os06t0329900-01 | Rice | cytosol | 30.34 | 24.04 |
TraesCS1D01G031100.1 | Wheat | peroxisome | 29.66 | 24.02 |
EER98034 | Sorghum | cytosol | 31.03 | 24.0 |
Zm00001d052828_P001 | Maize | cytosol | 30.0 | 23.9 |
TraesCS3D01G466800.1 | Wheat | cytosol | 13.1 | 23.9 |
OQU88491 | Sorghum | extracellular | 33.1 | 23.88 |
TraesCS3B01G513300.1 | Wheat | cytosol | 29.31 | 23.88 |
TraesCS3D01G463700.1 | Wheat | cytosol | 28.28 | 23.84 |
HORVU3Hr1G091690.3 | Barley | cytosol, peroxisome | 29.66 | 23.82 |
TraesCS2D01G026400.1 | Wheat | cytosol | 31.03 | 23.81 |
TraesCS3B01G513800.1 | Wheat | peroxisome | 10.34 | 23.81 |
Zm00001d015220_P001 | Maize | cytosol | 22.41 | 23.81 |
KXG19297 | Sorghum | cytosol | 30.0 | 23.71 |
HORVU3Hr1G100080.1 | Barley | cytosol | 29.31 | 23.68 |
TraesCSU01G051200.1 | Wheat | cytosol | 28.28 | 23.63 |
TraesCS3B01G421400.1 | Wheat | cytosol | 28.62 | 23.51 |
TraesCS7A01G224900.1 | Wheat | peroxisome | 20.34 | 23.51 |
TraesCS3B01G512900.1 | Wheat | cytosol | 28.97 | 23.46 |
HORVU3Hr1G081480.2 | Barley | plastid | 28.97 | 23.27 |
TraesCS3A01G387300.1 | Wheat | cytosol | 28.97 | 23.27 |
HORVU3Hr1G100240.10 | Barley | cytosol | 30.0 | 23.26 |
TraesCS2D01G151700.1 | Wheat | cytosol | 29.31 | 23.22 |
EES15454 | Sorghum | cytosol | 32.07 | 23.19 |
KXG29202 | Sorghum | cytosol | 29.66 | 23.18 |
Zm00001d052827_P001 | Maize | cytosol | 30.34 | 23.04 |
Zm00001d052831_P001 | Maize | cytosol | 31.03 | 23.02 |
TraesCS3B01G421500.3 | Wheat | cytosol | 28.62 | 22.99 |
TraesCS3A01G411500.2 | Wheat | cytosol | 28.28 | 22.84 |
TraesCS3B01G514000.1 | Wheat | cytosol | 9.66 | 22.76 |
HORVU3Hr1G100060.1 | Barley | peroxisome, plastid | 30.0 | 22.66 |
OQU76323 | Sorghum | cytosol | 28.28 | 22.65 |
TraesCS3D01G462800.1 | Wheat | cytosol | 27.93 | 22.63 |
KXG19886 | Sorghum | cytosol | 27.93 | 22.44 |
CDY53071 | Canola | cytosol | 24.14 | 22.36 |
Zm00001d036164_P001 | Maize | cytosol | 27.93 | 22.31 |
Os05t0102000-01 | Rice | cytosol | 28.62 | 22.25 |
GSMUA_AchrUn_... | Banana | cytosol | 33.79 | 22.22 |
KRH00867 | Soybean | cytosol | 33.79 | 21.97 |
TraesCS3A01G471200.1 | Wheat | cytosol | 27.24 | 21.88 |
TraesCS3A01G470800.1 | Wheat | cytosol | 17.93 | 21.49 |
EES18827 | Sorghum | cytosol | 28.97 | 21.48 |
HORVU5Hr1G124360.1 | Barley | plastid | 30.34 | 21.46 |
TraesCS3D01G406500.1 | Wheat | plastid | 28.28 | 21.3 |
OQU88585 | Sorghum | plastid | 33.1 | 21.01 |
OQU86548 | Sorghum | cytosol | 26.55 | 20.32 |
Zm00001d035767_P001 | Maize | cytosol | 27.24 | 20.26 |
KXG19154 | Sorghum | plastid | 26.9 | 20.16 |
TraesCS3B01G444900.1 | Wheat | cytosol | 11.03 | 19.88 |
TraesCS5D01G193400.1 | Wheat | cytosol | 13.1 | 19.59 |
OQU86546 | Sorghum | cytosol | 24.83 | 18.37 |
Os11t0256900-01 | Rice | cytosol | 9.66 | 17.5 |
HORVU5Hr1G041680.2 | Barley | cytosol | 12.76 | 16.02 |
Protein Annotations
Gene3D:1.10.1200.270 | Gene3D:3.40.50.150 | MapMan:50.2.1 | GO:A0A078I6T9 | UniProt:A0A078I6T9 | EnsemblPlants:CDY44848 |
ProteinID:CDY44848 | ProteinID:CDY44848.1 | GO:GO:0003674 | GO:GO:0003824 | GO:GO:0008150 | GO:GO:0008152 |
GO:GO:0008168 | GO:GO:0016740 | GO:GO:0032259 | EnsemblPlantsGene:GSBRNA2T00080895001 | InterPro:MeTrfase_7 | PFAM:PF03492 |
PANTHER:PTHR31009 | PANTHER:PTHR31009:SF19 | InterPro:SAM-dependent_MTases | SUPFAM:SSF53335 | UniParc:UPI0004EB46B7 | SEG:seg |
Description
BnaC09g50480DBnaC09g50480D protein [Source:UniProtKB/TrEMBL;Acc:A0A078I6T9]
Coordinates
chrLK032604:+:6020..7365
Molecular Weight (calculated)
32924.4 Da
IEP (calculated)
4.761
GRAVY (calculated)
-0.323
Length
290 amino acids
Sequence
(BLAST)
(BLAST)
001: MMTNLDFPEC IKLTDLGCSS GQNTFLFMSE IINTISMLCQ ERNQNPPDID CCLNDLPGND FNTTFKFISF FNEKLTSKTP CFVSGVPGTK LMTMEFWSCK
101: VPEGLEKKKI SVYITSSSSQ SDYKAYKNQF QKDFTTFLRM RSEEMISNGR MVLTLIGRKT LDDPLYRDCC HFMTLLSDSL RDLVFEGLVS ASKANSFKMP
201: YYDPTDEEVN EIIKNEGSFQ INDLETHAFD LGHCKGESSL QSCGAKPGEK EANCMRAVSE KMLVAHFQDA INIDTMFQKY AQLLDKLEVT
101: VPEGLEKKKI SVYITSSSSQ SDYKAYKNQF QKDFTTFLRM RSEEMISNGR MVLTLIGRKT LDDPLYRDCC HFMTLLSDSL RDLVFEGLVS ASKANSFKMP
201: YYDPTDEEVN EIIKNEGSFQ INDLETHAFD LGHCKGESSL QSCGAKPGEK EANCMRAVSE KMLVAHFQDA INIDTMFQKY AQLLDKLEVT
001: MDSRFTDSTT TLRCNGKSEN ERKNGDEERI SKYSFVSPLC MRGGDGYNSY SSNSLLQRRV LSKAKPVLVK NTKDLMINLN FPTYIKVADL GCSSGQNTFL
101: AMSEIINTIN VFCQQRNQNP PEIDCCLNDL PSNDFNTTFK FIQFFNGMNI TSKESYFVYG VPGSFYSRLF PRRSLHFVHS SYGLHWLSKV PEGLEKNKMS
201: VYITNSSPLS TYKAYLNQFQ RDFATFLKLR SEEMVSNGRM VLTFIGRNTI DNPLHRDCCH FWTLLSKSLR DLVAEGLVSA SKVDSFYLPF YDPNEKEIKE
301: MVQKEGSFEI RDLETHGYDL GHCNQDESKR SKSGQNEANY IRAVSEPLLA AHFGDAIINI LFNKFACHVS QHVSCRNKTT VSIVVSLTKK KTFLMS
101: AMSEIINTIN VFCQQRNQNP PEIDCCLNDL PSNDFNTTFK FIQFFNGMNI TSKESYFVYG VPGSFYSRLF PRRSLHFVHS SYGLHWLSKV PEGLEKNKMS
201: VYITNSSPLS TYKAYLNQFQ RDFATFLKLR SEEMVSNGRM VLTFIGRNTI DNPLHRDCCH FWTLLSKSLR DLVAEGLVSA SKVDSFYLPF YDPNEKEIKE
301: MVQKEGSFEI RDLETHGYDL GHCNQDESKR SKSGQNEANY IRAVSEPLLA AHFGDAIINI LFNKFACHVS QHVSCRNKTT VSIVVSLTKK KTFLMS
Arabidopsis Description
NAMT1S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Source:UniProtKB/TrEMBL;Acc:Q0WL44]
SUBAcon: [cytosol]
SUBAcon: [cytosol]
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.