Subcellular Localization
min:
: max
Winner_takes_all: nucleus
Predictor Summary:
Predictor Summary:
- nucleus 5
- plasma membrane 2
- extracellular 1
- endoplasmic reticulum 1
- vacuole 1
- golgi 1
| Predictors | GFP | MS/MS | Papers | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PPI
Inferred distinct locusB in Crop
| locusB | locations |
|---|---|
| PGSC0003DMT400043112 |
Inferred from Arabidopsis experimental PPI
| Ath locusA | locusB | Ath locusB | Paper |
|---|---|---|---|
| AT4G21070.1 | PGSC0003DMT400043112 | AT4G04020.1 | 16957774 |
Homology
Paralog
| locus | Identity | Homology Identity |
|---|
Ortholog
| locus | Homology Species | Location | Identity | Homology Identity |
|---|---|---|---|---|
| Solyc08g023280.2.1 | Tomato | nucleus | 87.8 | 92.99 |
| Bra037622.1-P | Field mustard | nucleus | 2.84 | 54.55 |
| HORVU4Hr1G010810.1 | Barley | cytosol | 2.08 | 46.81 |
| CDX76414 | Canola | nucleus | 33.68 | 39.73 |
| Bra020883.1-P | Field mustard | nucleus | 33.49 | 39.42 |
| CDY57063 | Canola | nucleus | 32.92 | 37.78 |
| AT4G21070.1 | Thale cress | nucleus | 33.59 | 37.73 |
| CDX82797 | Canola | nucleus | 31.98 | 37.51 |
| CDX79031 | Canola | nucleus | 32.36 | 36.85 |
| GSMUA_Achr6P29980_001 | Banana | nucleus | 31.6 | 34.08 |
| TraesCS1A01G329600.1 | Wheat | nucleus | 31.41 | 33.5 |
| Os05t0512000-01 | Rice | extracellular | 31.13 | 33.33 |
| EES18483 | Sorghum | nucleus | 31.22 | 33.13 |
| HORVU1Hr1G077590.4 | Barley | plastid | 31.32 | 32.74 |
| TraesCS1B01G343100.2 | Wheat | nucleus | 30.37 | 32.07 |
| TraesCS1D01G331700.1 | Wheat | nucleus | 29.14 | 32.02 |
| Zm00001d038667_P001 | Maize | nucleus | 27.53 | 31.66 |
| PGSC0003DMT400038153 | Potato | endoplasmic reticulum, extracellular, golgi, nucleus, plasma membrane, vacuole | 19.3 | 28.94 |
| KRH11144 | Soybean | endoplasmic reticulum, extracellular, golgi, nucleus, plasma membrane, vacuole | 37.56 | 27.8 |
Protein Annotations
| EntrezGene:102579131 | MapMan:14.3.1.1 | Gene3D:3.30.40.10 | Gene3D:3.40.50.10190 | InterPro:BRCA1-associated | InterPro:BRCT_dom |
| InterPro:BRCT_dom_sf | ncoils:Coil | InterPro:EPHD | GO:GO:0000724 | GO:GO:0003674 | GO:GO:0003824 |
| GO:GO:0004842 | GO:GO:0005488 | GO:GO:0005575 | GO:GO:0005622 | GO:GO:0005623 | GO:GO:0005634 |
| GO:GO:0006139 | GO:GO:0006259 | GO:GO:0006281 | GO:GO:0006310 | GO:GO:0006464 | GO:GO:0006950 |
| GO:GO:0006974 | GO:GO:0008150 | GO:GO:0008152 | GO:GO:0009628 | GO:GO:0009987 | GO:GO:0010332 |
| GO:GO:0016567 | GO:GO:0016740 | GO:GO:0019538 | GO:GO:0046872 | GO:GO:0071480 | InterPro:IPR001357 |
| InterPro:IPR001841 | InterPro:IPR013083 | InterPro:IPR034732 | InterPro:IPR036420 | UniProt:M1A3A6 | PFAM:PF00533 |
| PFAM:PF13771 | PFAM:PF13923 | EnsemblPlantsGene:PGSC0003DMG400005381 | PGSC:PGSC0003DMG400005381 | EnsemblPlants:PGSC0003DMT400013749 | ScanProsite:PS00518 |
| PFscan:PS50089 | PFscan:PS50172 | PFscan:PS51805 | PANTHER:PTHR13763 | PANTHER:PTHR13763:SF1 | SMART:SM00184 |
| SMART:SM00249 | SMART:SM00292 | SUPFAM:SSF52113 | SUPFAM:SSF57850 | UniParc:UPI000295B230 | InterPro:Znf_PHD |
| InterPro:Znf_RING | InterPro:Znf_RING/FYVE/PHD | InterPro:Znf_RING_CS | SEG:seg | : | : |
Description
Brca1 associated ring domain [Source:PGSC_GENE;Acc:PGSC0003DMG400005381]
Coordinates
chr8:+:28473449..28479349
Molecular Weight (calculated)
116451.0 Da
IEP (calculated)
8.816
GRAVY (calculated)
-0.481
Length
1057 amino acids
Sequence
(BLAST)
(BLAST)
0001: MADISHLERM GRELKCPICL SLLNSAVSLT CNHVFCNLCI QTGMKSGSNC PVCKVPFHRR EIRPALHMDN LVSIYKNMEI ASGVNMFLTQ SNPSSKLPGE
0101: DTQSNGEKNC GFQETSKTVT EAPATGNQKR KRGKGSKKSS GCNKKISGSN LIRPSFPTKK RVQVPQYPPS ETPPPTKLVG GNGKSITDEV QKPLVIERDR
0201: SMLYEKGEPV LSPFFWLREE NIERSSQQTD GDIIMDTPPA VPSFSDMKDL DDEVHCEMSP KSGPYDAASG ADLFNSEMFD WTQRACSPEL CSSPFKMKLK
0301: DTIDSAGAQE KTQARSVEES GINASATENR TAVENEKGTD KGQLSSPALF PPENKTTSRK DVVCKSSRSK ALRISQKKQG KSIIGEVSEV HNASPKAAEK
0401: TMKNNQDNAN AFISNKKDLK NKKKGRSSRN VTGSVVEDIS TLCGAKRLRK GNNSKSFNLS TLVNQEKHSE GSVETLDLKT HNKLRKGSLS EQNKNCFGPK
0501: GGQKTAACNI PQTQDEALPF ESANRLIPMD NRKPTPSTKL KKCELGSGNK LHGKKKVKFS DNGQLADKDN ITLQKIQKRV HNSLETEKSV LNLNDSVLQK
0601: CEASQNQIQC AFCRSAEESE VSGVMVSYLN GNPVKEDVNG APGVIHVHKY CAEWAPNVYF GDDDVVNLES ELKRSRRITC FFCGVKGAAL GCYETSCRKS
0701: FHVPCAKLTP ECRWDSDNFV MLCPLHANSK LPCEIPGKQT KIGDSIKRNS RIHQPKVSAT PDNAATLQWK SQKKNKNLVL CCSALTADEK ELVSTLKRLS
0801: GVTVVKNWDL SVTHVIASTD EKGACRRTLK YLMGVLAGKW IMSIDWIIAS LEATEFIDEQ QYEIKIDTHG IVDGPKLGRL RILNKVTSFS RFIVNNKLIK
0901: CISICLDNSC YSCLTAFSSS ASCSYIICEG PVMHSLNIKI PVLQQPKLFN GYKFFFMGDF LPSYKSYLHD LVIAAGGIVL NRKPIAVDQE ILSPGCSPPF
1001: VIYSHEQLDQ CEGSEKISII VRRRSDAEVL ASSTGAVAAS NSWILNCIAG SRLLELE
0101: DTQSNGEKNC GFQETSKTVT EAPATGNQKR KRGKGSKKSS GCNKKISGSN LIRPSFPTKK RVQVPQYPPS ETPPPTKLVG GNGKSITDEV QKPLVIERDR
0201: SMLYEKGEPV LSPFFWLREE NIERSSQQTD GDIIMDTPPA VPSFSDMKDL DDEVHCEMSP KSGPYDAASG ADLFNSEMFD WTQRACSPEL CSSPFKMKLK
0301: DTIDSAGAQE KTQARSVEES GINASATENR TAVENEKGTD KGQLSSPALF PPENKTTSRK DVVCKSSRSK ALRISQKKQG KSIIGEVSEV HNASPKAAEK
0401: TMKNNQDNAN AFISNKKDLK NKKKGRSSRN VTGSVVEDIS TLCGAKRLRK GNNSKSFNLS TLVNQEKHSE GSVETLDLKT HNKLRKGSLS EQNKNCFGPK
0501: GGQKTAACNI PQTQDEALPF ESANRLIPMD NRKPTPSTKL KKCELGSGNK LHGKKKVKFS DNGQLADKDN ITLQKIQKRV HNSLETEKSV LNLNDSVLQK
0601: CEASQNQIQC AFCRSAEESE VSGVMVSYLN GNPVKEDVNG APGVIHVHKY CAEWAPNVYF GDDDVVNLES ELKRSRRITC FFCGVKGAAL GCYETSCRKS
0701: FHVPCAKLTP ECRWDSDNFV MLCPLHANSK LPCEIPGKQT KIGDSIKRNS RIHQPKVSAT PDNAATLQWK SQKKNKNLVL CCSALTADEK ELVSTLKRLS
0801: GVTVVKNWDL SVTHVIASTD EKGACRRTLK YLMGVLAGKW IMSIDWIIAS LEATEFIDEQ QYEIKIDTHG IVDGPKLGRL RILNKVTSFS RFIVNNKLIK
0901: CISICLDNSC YSCLTAFSSS ASCSYIICEG PVMHSLNIKI PVLQQPKLFN GYKFFFMGDF LPSYKSYLHD LVIAAGGIVL NRKPIAVDQE ILSPGCSPPF
1001: VIYSHEQLDQ CEGSEKISII VRRRSDAEVL ASSTGAVAAS NSWILNCIAG SRLLELE
001: MADTSHLERM GRELKCPICL SLYNSAVSLS CNHVFCNACI VKSMKMDATC PVCKIPYHRR EIRGAPHMDS LVSIYKNMED ASGIKLFVSQ NNPSPSDKEK
101: QVRDASVEKA SDKNRQGSRK GRASKRNEYG KTKEIDVDAP GPIVMKPSSQ TKKRVQLLQN LSAESLTKPT ESVETAEKPK DYTENTVIRL DEHPSLNKEG
201: NLSPFFWLRD EDDGENSSQR TESDQLLGTT PVNVPSFSDL MDSDHESPSK EDEQQKPNPG DMFDSEMFEW TQRPCSPEIL PSPVKAKVLG RDEIDLTQKK
301: LPKVKVASSK CKNRKAGSAR NTVARRSIGV SQEDNMESSA AATISEQQDS RGTSGTIIRN DVNTDENVKA KRATRSKAQS TRVQSDLNVS NEADGKQGTK
401: RKRSSIKSSP AHPIAGPNEL SLGTEIVGKG DQDQAHGPSD THPEKRSPTE KPSLKKRGRK SNASSSLKDL SGKTQKKTSE KKLKLDSHMI SSKATQPHGN
501: GILTAGLNQG GDKQDSRNNR KSTVGKDDHT MQVIEKCSTI NKSSSGGSAH LRRCNGSLTK KFTCAFCQCS EDTEASGEMT HYYRGEPVSA DFNGGSKVIH
601: VHKNCAEWAP NVYFNDLTIV NLDVELTRSR RISCSCCGLK GAALGCYNKS CKNSFHVTCA KLIPECRWDN VKFVMLCPLD ASIKLPCEEA NSKDRKCKRT
701: PKEPLHSQPK QVSGKANIRE LHIKQFHGFS KKLVLSCSGL TVEEKTVIAE FAELSGVTIS KNWDSTVTHV IASINENGAC KRTLKFMMAI LEGKWILTID
801: WIKACMKNTK YVSEEPYEIT MDVHGIREGP YLGRQRALKK KPKLFTGLKF YIMGDFELAY KGYLQDLIVA AGGTILRRRP VSSDDNEAST IVVFSVEPSK
901: KKTLTQRRSD AEALAKSARA RAASSSWVLD SIAGCQILVL I
101: QVRDASVEKA SDKNRQGSRK GRASKRNEYG KTKEIDVDAP GPIVMKPSSQ TKKRVQLLQN LSAESLTKPT ESVETAEKPK DYTENTVIRL DEHPSLNKEG
201: NLSPFFWLRD EDDGENSSQR TESDQLLGTT PVNVPSFSDL MDSDHESPSK EDEQQKPNPG DMFDSEMFEW TQRPCSPEIL PSPVKAKVLG RDEIDLTQKK
301: LPKVKVASSK CKNRKAGSAR NTVARRSIGV SQEDNMESSA AATISEQQDS RGTSGTIIRN DVNTDENVKA KRATRSKAQS TRVQSDLNVS NEADGKQGTK
401: RKRSSIKSSP AHPIAGPNEL SLGTEIVGKG DQDQAHGPSD THPEKRSPTE KPSLKKRGRK SNASSSLKDL SGKTQKKTSE KKLKLDSHMI SSKATQPHGN
501: GILTAGLNQG GDKQDSRNNR KSTVGKDDHT MQVIEKCSTI NKSSSGGSAH LRRCNGSLTK KFTCAFCQCS EDTEASGEMT HYYRGEPVSA DFNGGSKVIH
601: VHKNCAEWAP NVYFNDLTIV NLDVELTRSR RISCSCCGLK GAALGCYNKS CKNSFHVTCA KLIPECRWDN VKFVMLCPLD ASIKLPCEEA NSKDRKCKRT
701: PKEPLHSQPK QVSGKANIRE LHIKQFHGFS KKLVLSCSGL TVEEKTVIAE FAELSGVTIS KNWDSTVTHV IASINENGAC KRTLKFMMAI LEGKWILTID
801: WIKACMKNTK YVSEEPYEIT MDVHGIREGP YLGRQRALKK KPKLFTGLKF YIMGDFELAY KGYLQDLIVA AGGTILRRRP VSSDDNEAST IVVFSVEPSK
901: KKTLTQRRSD AEALAKSARA RAASSSWVLD SIAGCQILVL I
Arabidopsis Description
BRCA1Protein BREAST CANCER SUSCEPTIBILITY 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q8RXD4]
SUBAcon: [nucleus]
SUBAcon: [nucleus]
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.