Factsheet for PGSC0003DMT400041701

Subcellular Localization

min:

: max

Winner_takes_all: cytosol

Predictor Summary:

cytosol 4
mitochondrion 2
golgi 1
cytoskeleton 1

Predictors

GFP

MS/MS

Papers

PPI

No PPI Data

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
Solyc11g008870.1.1	Tomato	extracellular, plastid	98.48	98.48
PGSC0003DMT400060046	Potato	cytosol	88.55	88.11
VIT_15s0024g00070.t01	Wine grape	cytosol	84.51	84.51
GSMUA_Achr11P...	Banana	cytosol	78.28	83.94
KRH64810	Soybean	cytosol, endoplasmic reticulum, nucleus	84.18	83.89
KRH56478	Soybean	cytosol, nucleus	84.01	83.87
GSMUA_Achr7P21790_001	Banana	cytosol	83.17	83.03
Zm00001d012999_P001	Maize	cytosol	39.73	82.23
EER90654	Sorghum	cytosol	81.48	81.62
TraesCS5B01G481000.1	Wheat	cytosol	81.48	81.48
TraesCS5D01G481300.1	Wheat	cytosol	81.31	81.31
TraesCS5A01G468400.1	Wheat	cytosol, golgi, unclear	81.31	81.31
Os03t0815200-01	Rice	cytosol, extracellular, nucleus, plasma membrane	81.31	81.31
HORVU5Hr1G111620.1	Barley	cytosol	81.31	81.31
AT2G44160.1	Thale cress	cytosol	80.47	80.47
CDX79777	Canola	cytosol	80.3	80.17
CDY17879	Canola	cytosol	80.13	80.13
CDY41193	Canola	cytosol	79.8	80.07
Bra004810.1-P	Field mustard	cytosol	74.92	80.04
Bra007497.1-P	Field mustard	cytosol	79.63	79.9
CDX71855	Canola	cytosol	79.46	79.73
CDX67820	Canola	cytosol	78.45	78.72
Bra003397.1-P	Field mustard	cytosol	78.45	78.72
CDX98401	Canola	cytosol	78.45	78.72
CDY30457	Canola	cytosol	78.79	78.66
Bra037664.1-P	Field mustard	cytosol	78.62	78.49
CDY23420	Canola	cytosol	78.62	78.49
AT3G59970.3	Thale cress	cytosol	78.11	78.38
Zm00001d034602_P003	Maize	cytosol	78.11	74.24
VIT_05s0094g01600.t01	Wine grape	cytosol	9.6	69.51
Zm00001d042247_P001	Maize	extracellular, golgi	9.76	49.57
Zm00001d013002_P001	Maize	golgi, mitochondrion	9.43	47.86

Protein Annotations

KEGG:00670+1.5.1.20	KEGG:00720+1.5.1.20	EntrezGene:102598073	Gene3D:3.20.20.220	MapMan:7.5.7.4	InterPro:FAD-linked_oxidoreductase-like
InterPro:Fadh2_euk	GO:GO:0003674	GO:GO:0003824	GO:GO:0004489	GO:GO:0006555	GO:GO:0008150
GO:GO:0008152	GO:GO:0009987	GO:GO:0016491	GO:GO:0035999	GO:GO:0055114	UniProt:M1BBU4
InterPro:Mehydrof_redctse	PFAM:PF02219	EnsemblPlantsGene:PGSC0003DMG400016168	PGSC:PGSC0003DMG400016168	EnsemblPlants:PGSC0003DMT400041701	PANTHER:PTHR21091
PANTHER:PTHR21091:SF31	SUPFAM:SSF51730	TIGRFAMs:TIGR00677	UniParc:UPI000295F65F	RefSeq:XP_006353237.1	:

Description

Methylenetetrahydrofolate reductase [Source:PGSC_GENE;Acc:PGSC0003DMG400016168]

Coordinates

chr11:+:2969799..2974732

Molecular Weight (calculated)

67186.6 Da

IEP (calculated)

5.587

GRAVY (calculated)

-0.268

Length

594 amino acids

Sequence
(BLAST)

001: MKVIEKIQEA AKTDKVIFSF EFFPPKTDDG VENLFERMER MVAHSPSFCD ITWGAGGSTA DLTLDIVNRM QNMVCVESMM HLTCTNMPVE KIDHALDTIK
101: ANGIQNVLAL RGDPPHGQDK FVQVEGGFAC ALDLVKHMRA KYGDYFGITV AGYPEAHPDV IPANGIATKE IYENDLAYLK KKVDAGADVI VTQLFYDTDV
201: FLKFVNDCRQ IGINCPIVPG IMPINNYKGF LRMTGFCKTK IPEEIMAALE PIKDNEEAVK AYGIHLGTEM CKKILATGIK TLHLYTLNME KSALAILMNL
301: GLIEESKISR PLPWRRPANV FRVKEDVRPI FWANRPKSYI SRTTGWDEYP HGRWSNAQNP SYGALTDYQF MRARSRDKKL QEEWAVALNS VEDIYEKFKD
401: YCLGKLRSCP WSELDGLQPE TKIINEKLGQ VNTKGFLTIN SQPAVNAEKS DSPSVGWGGP GGYVYQKAYL ELFCSQEKLN ALVEKCKSFP YLTYMAVNKE
501: GNWISNVNQT DVNAVTWGVF PAKEIIQPTV VDPASFMVWK DEAFEIWSRG WAQLYPETDP SRKLLEQVQN SYFLVSLVDN DYINGDLFSI FKDI

Best Arabidopsis Sequence Match ( AT2G44160.1 )
(BLAST)

001: MKVIDKIQSL ADEGKTAFSF EFFPPKTEDG VDNLFERMDR MVAYGPTFCD ITWGAGGSTA DLTLDIASRM QNVVCVESMM HLTCTNMPVE KIDHALETIR
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFDC ALDLVNHIRS KYGDYFGITV AGYPEAHPDV IGENGLASNE AYQSDLEYLK KKIDAGADLI VTQLFYDTDI
201: FLKFVNDCRQ IGISCPIVPG IMPINNYRGF LRMTGFCKTK IPVEVMAALE PIKDNEEAVK AYGIHLGTEM CKKMLAHGVK SLHLYTLNME KSALAILMNL
301: GMIDESKISR SLPWRRPANV FRTKEDVRPI FWANRPKSYI SRTKGWEDFP QGRWGDSRSA SYGALSDHQF SRPRARDKKL QQEWVVPLKS VEDIQEKFKE
401: LCLGNLKSSP WSELDGLQPE TRIINEQLIK VNSKGFLTIN SQPSVNAERS DSPTVGWGGP VGYVYQKAYL EFFCSKEKLD AVVEKCKALP SITYMAVNKG
501: EQWVSNTAQA DVNAVTWGVF PAKEIIQPTI VDPASFNVWK DEAFETWSRS WANLYPEADP SRNLLEEVKN SYYLVSLVEN DYINGDIFAV FADL

Arabidopsis Description

MTHFR2Methylenetetrahydrofolate reductase 2 [Source:UniProtKB/Swiss-Prot;Acc:O80585]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.