Factsheet for PGSC0003DMT400060046

Subcellular Localization

min:

: max

Winner_takes_all: cytosol

Predictor Summary:

cytosol 5
mitochondrion 2
plastid 1

Predictors

GFP

MS/MS

Papers

PPI

No PPI Data

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
Solyc05g055730.2.1	Tomato	cytosol, unclear	98.16	98.32
PGSC0003DMT400041701	Potato	cytosol	88.11	88.55
Zm00001d012999_P001	Maize	cytosol	40.37	83.97
VIT_15s0024g00070.t01	Wine grape	cytosol	82.75	83.17
KRH64810	Soybean	cytosol, endoplasmic reticulum, nucleus	82.91	83.05
KRH56478	Soybean	cytosol, nucleus	82.75	83.03
Os03t0815200-01	Rice	cytosol, extracellular, nucleus, plasma membrane	82.24	82.66
GSMUA_Achr11P...	Banana	cytosol	76.05	81.95
EER90654	Sorghum	cytosol	81.24	81.79
GSMUA_Achr7P21790_001	Banana	cytosol	81.24	81.51
TraesCS5A01G468400.1	Wheat	cytosol, golgi, unclear	79.9	80.3
TraesCS5B01G481000.1	Wheat	cytosol	79.9	80.3
TraesCS5D01G481300.1	Wheat	cytosol	79.9	80.3
HORVU5Hr1G111620.1	Barley	cytosol	79.56	79.97
CDY41193	Canola	cytosol	78.73	79.39
Bra007497.1-P	Field mustard	cytosol	78.56	79.22
CDX71855	Canola	cytosol	78.39	79.05
AT2G44160.1	Thale cress	cytosol	78.06	78.45
CDX98401	Canola	cytosol	77.55	78.21
CDX67820	Canola	cytosol	77.39	78.04
Bra003397.1-P	Field mustard	cytosol	77.39	78.04
AT3G59970.3	Thale cress	cytosol	77.05	77.7
Bra004810.1-P	Field mustard	cytosol	72.36	77.7
CDY17879	Canola	cytosol	77.22	77.61
CDX79777	Canola	cytosol	77.22	77.48
CDY30457	Canola	cytosol	75.71	75.97
CDY23420	Canola	cytosol	75.54	75.8
Bra037664.1-P	Field mustard	cytosol	75.54	75.8
Zm00001d034602_P003	Maize	cytosol	78.06	74.56
VIT_05s0094g01600.t01	Wine grape	cytosol	9.05	65.85
Zm00001d042247_P001	Maize	extracellular, golgi	9.72	49.57
Zm00001d013002_P001	Maize	golgi, mitochondrion	9.38	47.86

Protein Annotations

KEGG:00670+1.5.1.20	KEGG:00720+1.5.1.20	EntrezGene:102596086	Gene3D:3.20.20.220	MapMan:7.5.7.4	InterPro:FAD-linked_oxidoreductase-like
InterPro:Fadh2_euk	GO:GO:0003674	GO:GO:0003824	GO:GO:0004489	GO:GO:0006555	GO:GO:0008150
GO:GO:0008152	GO:GO:0009987	GO:GO:0016491	GO:GO:0035999	GO:GO:0055114	UniProt:M1C552
InterPro:Mehydrof_redctse	PFAM:PF02219	EnsemblPlantsGene:PGSC0003DMG400023361	PGSC:PGSC0003DMG400023361	EnsemblPlants:PGSC0003DMT400060046	PANTHER:PTHR21091
PANTHER:PTHR21091:SF31	SUPFAM:SSF51730	TIGRFAMs:TIGR00677	UniParc:UPI000295B13E	RefSeq:XP_006345827.1	:

Description

Methylenetetrahydrofolate reductase [Source:PGSC_GENE;Acc:PGSC0003DMG400023361]

Coordinates

chr5:-:51359496..51365523

Molecular Weight (calculated)

67624.3 Da

IEP (calculated)

5.563

GRAVY (calculated)

-0.220

Length

597 amino acids

Sequence
(BLAST)

001: MKVIEKIQES VKDDRVVFSF EFFPPKTEDG VDNLFERMER MVSHNPSFCD ITWGAGGSTA DLTLEISNRM QNMVCVETMM HLTCTNMPVE KIDHALETIK
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFAC ALDLVKHMRA KYGDYFGITV AGYPEAHPDV IPATGLATLE TYENELAYLK QKVDAGADLI VTQLFYDTDN
201: FLKFVSDCRQ IGITCPIVPG IMPINNYKGF LRMTGFCKTR IPAEITAALE PIKDNEEAVK AYGIHLGTEM CKKIMASGIK TLHLYTLNME KSALAILMNL
301: GLIEESKISR PLPWRRPTNV FRIKEDVRPI FWANRPKSYI SRTIGWDEFP HGRWGNAKNP SYGALSDYQF MRARSRDKKL QEEWAIALNS VEDIYERFMN
401: YCLGKLRSCP WSELDGLQAE TKIIDDHLGN INSKGFLTIN SQPSVNGAKS DAPLVGWGGP GGFVYQKAYL EFFCSREKLN AVIEKCMAFP FLTYMAVNKK
501: GNWMSNVNQV DVNAVTWGVF PAKEIVQPTV VDPASFMVWK DEAFEIWSRG WAQLYPENDP SRTLLEQVQN SYFLVSLVDN DYINGDLFAI FKDMIWN

Best Arabidopsis Sequence Match ( AT2G44160.1 )
(BLAST)

001: MKVIDKIQSL ADEGKTAFSF EFFPPKTEDG VDNLFERMDR MVAYGPTFCD ITWGAGGSTA DLTLDIASRM QNVVCVESMM HLTCTNMPVE KIDHALETIR
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFDC ALDLVNHIRS KYGDYFGITV AGYPEAHPDV IGENGLASNE AYQSDLEYLK KKIDAGADLI VTQLFYDTDI
201: FLKFVNDCRQ IGISCPIVPG IMPINNYRGF LRMTGFCKTK IPVEVMAALE PIKDNEEAVK AYGIHLGTEM CKKMLAHGVK SLHLYTLNME KSALAILMNL
301: GMIDESKISR SLPWRRPANV FRTKEDVRPI FWANRPKSYI SRTKGWEDFP QGRWGDSRSA SYGALSDHQF SRPRARDKKL QQEWVVPLKS VEDIQEKFKE
401: LCLGNLKSSP WSELDGLQPE TRIINEQLIK VNSKGFLTIN SQPSVNAERS DSPTVGWGGP VGYVYQKAYL EFFCSKEKLD AVVEKCKALP SITYMAVNKG
501: EQWVSNTAQA DVNAVTWGVF PAKEIIQPTI VDPASFNVWK DEAFETWSRS WANLYPEADP SRNLLEEVKN SYYLVSLVEN DYINGDIFAV FADL

Arabidopsis Description

MTHFR2Methylenetetrahydrofolate reductase 2 [Source:UniProtKB/Swiss-Prot;Acc:O80585]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.