Factsheet for Solyc05g055730.2.1

Subcellular Localization

min:

: max

Winner_takes_all: unclear, cytosol

Predictor Summary:

cytosol 5
mitochondrion 2

Predictors

GFP

MS/MS

Papers

Winner Takes All:	cytosol, unclear
Any Predictor:	cytosol, mitochondrion
BaCelLo:	cytosol
EpiLoc:	mitochondrion
MultiLoc:	cytosol
Plant-mPloc:	cytosol
PProwler:	mitochondrion
WoLF PSORT:	cytosol
YLoc:	cytosol

unclear: 26455813

msms PMID: 26455813 doi

P Paul, P Chaturvedi, M Selymesi, A Ghatak, A Mesihovic, KD Scharf, W Weckwerth, S Simm, E Schleiff

Goethe University, Department of Biosciences, Molecular Cell Biology of Plants, Frankfurt/Main, Germany., Goethe University, Department of Biosciences, Molecular Cell Biology of Plants, Frankfurt/Main, Germany; SPOT-ITN Consortium., Goethe University, Department of Biosciences, Molecular Cell Biology of Plants, Frankfurt/Main, Germany; SPOT-ITN Consortium; Goethe University, Cluster of Excellence Frankfurt, Frankfurt/Main, Germany; Goethe University, Buchmann Institute of Molecular Life Sciences, Frankfurt/Main, Germany. Electronic address: schleiff@bio.uni-frankfurt.de., SPOT-ITN Consortium; University of Vienna, Department of Ecogenomics and Systems biology, Vienna, Austria., University of Vienna, Department of Ecogenomics and Systems biology, Vienna, Austria; School of Biotechnology and Bioinformatics, D.Y. Patil University, Mumbai, India.

PPI

No PPI Data

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
PGSC0003DMT400060046	Potato	cytosol	98.32	98.16
Solyc11g008870.1.1	Tomato	extracellular, plastid	87.58	87.88
Zm00001d012999_P001	Maize	cytosol	40.1	83.28
VIT_15s0024g00070.t01	Wine grape	cytosol	82.55	82.83
KRH64810	Soybean	cytosol, endoplasmic reticulum, nucleus	82.72	82.72
KRH56478	Soybean	cytosol, nucleus	82.55	82.69
Os03t0815200-01	Rice	cytosol, extracellular, nucleus, plasma membrane	81.88	82.15
GSMUA_Achr11P...	Banana	cytosol	76.01	81.77
GSMUA_Achr7P21790_001	Banana	cytosol	81.21	81.34
EER90654	Sorghum	cytosol	80.87	81.28
TraesCS5D01G481300.1	Wheat	cytosol	79.7	79.97
TraesCS5B01G481000.1	Wheat	cytosol	79.7	79.97
TraesCS5A01G468400.1	Wheat	cytosol, golgi, unclear	79.7	79.97
HORVU5Hr1G111620.1	Barley	cytosol	79.36	79.63
CDY41193	Canola	cytosol	78.36	78.89
Bra007497.1-P	Field mustard	cytosol	78.19	78.72
CDX71855	Canola	cytosol	78.02	78.55
AT2G44160.1	Thale cress	cytosol	78.19	78.45
CDX98401	Canola	cytosol	77.52	78.04
CDX67820	Canola	cytosol	77.35	77.87
Bra003397.1-P	Field mustard	cytosol	77.35	77.87
Bra004810.1-P	Field mustard	cytosol	72.48	77.7
CDY17879	Canola	cytosol	77.35	77.61
CDX79777	Canola	cytosol	77.35	77.48
AT3G59970.3	Thale cress	cytosol	76.85	77.36
CDY30457	Canola	cytosol	75.84	75.97
CDY23420	Canola	cytosol	75.67	75.8
Bra037664.1-P	Field mustard	cytosol	75.67	75.8
Zm00001d034602_P003	Maize	cytosol	77.68	74.08
VIT_05s0094g01600.t01	Wine grape	cytosol	9.06	65.85
Zm00001d042247_P001	Maize	extracellular, golgi	9.73	49.57
Zm00001d013002_P001	Maize	golgi, mitochondrion	9.4	47.86

Protein Annotations

KEGG:00670+1.5.1.20	KEGG:00720+1.5.1.20	Gene3D:3.20.20.220	MapMan:7.5.7.4	InterPro:FAD-linked_oxidoreductase-like	InterPro:Fadh2_euk
GO:GO:0003674	GO:GO:0003824	GO:GO:0004489	GO:GO:0005575	GO:GO:0005622	GO:GO:0005623
GO:GO:0005737	GO:GO:0005829	GO:GO:0006555	GO:GO:0006730	GO:GO:0008150	GO:GO:0008152
GO:GO:0009987	GO:GO:0016491	GO:GO:0035999	GO:GO:0055114	UniProt:K4C2P8	InterPro:Mehydrof_redctse
PFAM:PF02219	PANTHER:PTHR21091	PANTHER:PTHR21091:SF31	SUPFAM:SSF51730	EnsemblPlantsGene:Solyc05g055730.2	EnsemblPlants:Solyc05g055730.2.1
TIGRFAMs:TIGR00677	UniParc:UPI0002767253	:	:	:	:

Description

Methylenetetrahydrofolate reductase [Source:UniProtKB/TrEMBL;Acc:K4C2P8]

Coordinates

chr5:-:65253945..65259249

Molecular Weight (calculated)

67637.1 Da

IEP (calculated)

5.563

GRAVY (calculated)

-0.240

Length

596 amino acids

Sequence
(BLAST)

001: MKVIEKIQES VKDDRVVFSF EFFPPKTEDG VDNLFERMER MVSHNPSFCD ITWGAGGSTA DLTLEISNRM QNMVCVETMM HLTCTNMPVE KIDHALETIK
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFAC ALDLVKHMRA KYGDYFGITV AGYPEAHPDV IPANGLATLE TYENELAYLK QKVDAGADLV VTQLFYDTDN
201: FLKFVSDCRQ IGITCPIVPG IMPINNYKGF LRMTGFCKTR IPAEITAALE PIKDNEEAVK AYGIHLGTEM CKKIMASGIK TLHLYTLNME KSALAILMNL
301: GLIEESKISR LLPWRRPTNV FRIKEDVRPI FWANRPKSYI SRTIGWDEFP HGRWGNAKNP SYGALSDYQF MRARSRDKKL QEEWAIALNS VEDIYERFMY
401: YCLGKLRSCP WSELDGLQAE TKIIDDHLGN INSKGFLTIN SQPSVNGAKS DAPLVGWGGP GGYVYQKAYL EFFCSREKLN AVIEKCTAYP FLTYMAVNKK
501: GNWMSNFNQI DVNAVTWGVF PSKEIVQPTV VDPASFMVWK DEAFEIWSRG WAQLYPENDP SRTLLEQVQN SYFLVSLVDN DYINGDLFAI FKDIWN

Best Arabidopsis Sequence Match ( AT2G44160.1 )
(BLAST)

001: MKVIDKIQSL ADEGKTAFSF EFFPPKTEDG VDNLFERMDR MVAYGPTFCD ITWGAGGSTA DLTLDIASRM QNVVCVESMM HLTCTNMPVE KIDHALETIR
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFDC ALDLVNHIRS KYGDYFGITV AGYPEAHPDV IGENGLASNE AYQSDLEYLK KKIDAGADLI VTQLFYDTDI
201: FLKFVNDCRQ IGISCPIVPG IMPINNYRGF LRMTGFCKTK IPVEVMAALE PIKDNEEAVK AYGIHLGTEM CKKMLAHGVK SLHLYTLNME KSALAILMNL
301: GMIDESKISR SLPWRRPANV FRTKEDVRPI FWANRPKSYI SRTKGWEDFP QGRWGDSRSA SYGALSDHQF SRPRARDKKL QQEWVVPLKS VEDIQEKFKE
401: LCLGNLKSSP WSELDGLQPE TRIINEQLIK VNSKGFLTIN SQPSVNAERS DSPTVGWGGP VGYVYQKAYL EFFCSKEKLD AVVEKCKALP SITYMAVNKG
501: EQWVSNTAQA DVNAVTWGVF PAKEIIQPTI VDPASFNVWK DEAFETWSRS WANLYPEADP SRNLLEEVKN SYYLVSLVEN DYINGDIFAV FADL

Arabidopsis Description

MTHFR2Methylenetetrahydrofolate reductase 2 [Source:UniProtKB/Swiss-Prot;Acc:O80585]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.