Subcellular Localization
min:
: max
Winner_takes_all: plastid, cytosol
Predictor Summary:
Predictor Summary:
- plastid 2
- mitochondrion 1
- cytosol 2
Predictors | GFP | MS/MS | Papers | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PPI
No PPI Data
Homology
Paralog
locus | Identity | Homology Identity |
---|
Ortholog
locus | Homology Species | Location | Identity | Homology Identity |
---|---|---|---|---|
TraesCS2A01G518600.1 | Wheat | mitochondrion, plastid | 86.14 | 90.62 |
TraesCS2B01G547000.1 | Wheat | plastid | 86.14 | 90.47 |
TraesCS2D01G520000.1 | Wheat | plastid | 85.64 | 90.1 |
Os12t0446900-01 | Rice | cytosol | 71.29 | 82.92 |
CDX72487 | Canola | cytosol | 24.42 | 79.14 |
Bra011543.1-P | Field mustard | cytosol | 60.4 | 73.35 |
CDX89705 | Canola | cytosol | 61.55 | 72.57 |
VIT_18s0001g12940.t01 | Wine grape | cytosol | 60.07 | 72.51 |
KRH60811 | Soybean | nucleus | 62.71 | 71.7 |
Bra017662.1-P | Field mustard | cytosol | 59.57 | 71.63 |
KRH29421 | Soybean | cytosol | 62.38 | 71.59 |
AT2G16370.1 | Thale cress | cytosol | 61.06 | 71.29 |
CDY45317 | Canola | cytosol | 58.42 | 71.23 |
KRH24440 | Soybean | cytosol, nucleus | 61.88 | 70.75 |
Solyc01g109830.2.1 | Tomato | cytosol | 61.39 | 70.59 |
PGSC0003DMT400001937 | Potato | cytosol | 60.56 | 69.64 |
KRH51504 | Soybean | nucleus | 63.7 | 67.96 |
CDX69070 | Canola | mitochondrion, plastid | 61.22 | 67.45 |
AT4G34570.1 | Thale cress | mitochondrion | 61.06 | 65.49 |
CDX75443 | Canola | mitochondrion | 60.73 | 64.67 |
GSMUA_Achr2P14300_001 | Banana | cytosol | 53.14 | 63.76 |
Bra013079.1-P | Field mustard | cytosol | 60.73 | 59.55 |
CDY02264 | Canola | cytosol | 60.4 | 59.22 |
CDX83194 | Canola | cytosol | 39.27 | 55.61 |
Bra000581.1-P | Field mustard | cytosol | 41.25 | 55.31 |
AT2G21550.1 | Thale cress | cytosol, plasma membrane, plastid | 44.06 | 54.27 |
CDY21464 | Canola | cytosol | 25.25 | 50.33 |
Protein Annotations
KEGG:00240+2.1.1.45 | KEGG:00670+1.5.1.3 | KEGG:00670+1.5.1.3+2.1.1.45 | KEGG:00670+2.1.1.45 | KEGG:00790+1.5.1.3 | Gene3D:3.30.572.10 |
Gene3D:3.40.430.10 | MapMan:6.3.1.2 | MapMan:7.5.5 | UniProt:A0A287JIX6 | InterPro:DHFR-TS | InterPro:DHFR-like_dom_sf |
InterPro:DHFR_CS | InterPro:DHFR_dom | GO:GO:0003674 | GO:GO:0003824 | GO:GO:0004146 | GO:GO:0004799 |
GO:GO:0006139 | GO:GO:0006231 | GO:GO:0006730 | GO:GO:0008150 | GO:GO:0008152 | GO:GO:0008168 |
GO:GO:0009058 | GO:GO:0009165 | GO:GO:0009987 | GO:GO:0016491 | GO:GO:0016740 | GO:GO:0032259 |
GO:GO:0046654 | GO:GO:0055114 | EnsemblPlantsGene:HORVU2Hr1G114640 | EnsemblPlants:HORVU2Hr1G114640.8 | InterPro:IPR001796 | InterPro:IPR024072 |
InterPro:IPR036926 | HAMAP:MF_00008 | PFAM:PF00186 | PFAM:PF00303 | PIRSF:PIRSF000389 | PRINTS:PR00108 |
ScanProsite:PS00075 | ScanProsite:PS00091 | PFscan:PS51330 | PANTHER:PTHR11548 | PANTHER:PTHR11548:SF7 | SUPFAM:SSF53597 |
SUPFAM:SSF55831 | TIGRFAMs:TIGR03284 | InterPro:Thymidate_synth/dCMP_Mease | InterPro:Thymidate_synth/dCMP_Mease_sf | InterPro:Thymidylate_synthase | InterPro:Thymidylate_synthase_AS |
UniParc:UPI000B4739D5 | SEG:seg | : | : | : | : |
Description
Bifunctional dihydrofolate reductase-thymidylate synthase [Source:UniProtKB/TrEMBL;Acc:A0A287JIX6]
Coordinates
chrchr2H:+:732691141..732698514
Molecular Weight (calculated)
68413.0 Da
IEP (calculated)
9.518
GRAVY (calculated)
-0.438
Length
606 amino acids
Sequence
(BLAST)
(BLAST)
001: LLGFARADFP PPPPENANHS RRLPPPTPAP HRRPTAASAR ARRRGSRRSS HRRPPRGLPG TRTTTISRWP RLKSLEAINK LKSSCFHQSR MMADVTNGNS
101: HCDIQRKYQV VVAATREMGI GKDGALPWKL PSDLKFFKDL TMATSDPSKK NAVIMGRKTW ESIPTKFRPL PGRLNVILTR SGSSDYAKAE NVVTCGSLDS
201: SLELLASAPY SSTIEKAFLI GGGQVLRESL NASACEAIHL TDIESTIECD TFIPPIDPLI FHPWYSSSPV VENNIRHSFA TFVRVRKSAE EANDPNVNDT
301: KKEKFEIQIF SFLPKMIFEK HDEYQYLNLV QDILRTGARK NDRTGTGTIS KFGCQMRFNL RKNFPLLTTK RVFWRGVLEE LLWFISGSTN AKVLQEKNIR
401: IWDGNASREY LDSIGLSQRE EGDLGPVYGF QWRHFGAEYS DMHADYTGKG FDQLADVINK IKNNPDDRRI ILSAWNPTDL KKMALPPCHM FAQFYVENGE
501: LSCQMYQRSA DMGLGVPFNI ASYSLLTCMI AQVCDLSPGE FVHVIGDAHV YSTHVQALEE QLQKQPKPFP ILKINPLKKD IDSFVASDFK LACYDPHQKI
601: EMKMAV
101: HCDIQRKYQV VVAATREMGI GKDGALPWKL PSDLKFFKDL TMATSDPSKK NAVIMGRKTW ESIPTKFRPL PGRLNVILTR SGSSDYAKAE NVVTCGSLDS
201: SLELLASAPY SSTIEKAFLI GGGQVLRESL NASACEAIHL TDIESTIECD TFIPPIDPLI FHPWYSSSPV VENNIRHSFA TFVRVRKSAE EANDPNVNDT
301: KKEKFEIQIF SFLPKMIFEK HDEYQYLNLV QDILRTGARK NDRTGTGTIS KFGCQMRFNL RKNFPLLTTK RVFWRGVLEE LLWFISGSTN AKVLQEKNIR
401: IWDGNASREY LDSIGLSQRE EGDLGPVYGF QWRHFGAEYS DMHADYTGKG FDQLADVINK IKNNPDDRRI ILSAWNPTDL KKMALPPCHM FAQFYVENGE
501: LSCQMYQRSA DMGLGVPFNI ASYSLLTCMI AQVCDLSPGE FVHVIGDAHV YSTHVQALEE QLQKQPKPFP ILKINPLKKD IDSFVASDFK LACYDPHQKI
601: EMKMAV
001: MATTTLNDSV TTTLASEPQR TYQVVVAATK EMGIGKDGKL PWNLPTDLKF FKDITLTTSD SSKKNAVVMG RKTWESIPIK YRPLSGRLNV VLTRSGGFDI
101: ANTENVVTCS SVDSALDLLA APPYCLSIER VFVIGGGDIL REALNRPSCD AIHLTEIDTS VDCDTFIPAI DTSVYQPWSS SFPVTENGLR FCFTTFVRVK
201: SSADESSDES NGSQSLQFDG KKFLFLPKMV FDQHEEFLYL NMVEDIISNG NVKNDRTGTG TLSKFGCQMK FNLRRSFPLL TTKRVFWRGV VEELLWFISG
301: STNAKVLQEK GIHIWDGNAS REYLDGIGLT EREEGDLGPV YGFQWRHFGA KYTDMHADYT GQGFDQLVDV IDKIKNNPDD RRIIMSAWNP SDLKLMALPP
401: CHMFAQFYVA EGELSCQMYQ RSADMGLGVP FNIASYSLLT CMLAHVCDLV PGDFIHVLGD AHVYKTHVRP LQEQLLNLPK PFPVMKINPE KKQIDSFVAS
501: DFDLTGYDPH KKIEMKMAV
101: ANTENVVTCS SVDSALDLLA APPYCLSIER VFVIGGGDIL REALNRPSCD AIHLTEIDTS VDCDTFIPAI DTSVYQPWSS SFPVTENGLR FCFTTFVRVK
201: SSADESSDES NGSQSLQFDG KKFLFLPKMV FDQHEEFLYL NMVEDIISNG NVKNDRTGTG TLSKFGCQMK FNLRRSFPLL TTKRVFWRGV VEELLWFISG
301: STNAKVLQEK GIHIWDGNAS REYLDGIGLT EREEGDLGPV YGFQWRHFGA KYTDMHADYT GQGFDQLVDV IDKIKNNPDD RRIIMSAWNP SDLKLMALPP
401: CHMFAQFYVA EGELSCQMYQ RSADMGLGVP FNIASYSLLT CMLAHVCDLV PGDFIHVLGD AHVYKTHVRP LQEQLLNLPK PFPVMKINPE KKQIDSFVAS
501: DFDLTGYDPH KKIEMKMAV
Arabidopsis Description
THY-1Bifunctional dihydrofolate reductase-thymidylate synthase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q05762]
SUBAcon: [cytosol]
SUBAcon: [cytosol]
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.