Subcellular Localization
min:
: max
Winner_takes_all: mitochondrion
Predictor Summary:
Predictor Summary:
- plastid 3
- mitochondrion 5
- plasma membrane 1
PPI
No PPI Data
Homology
Paralog
| locus | Identity | Homology Identity |
|---|
Ortholog
| locus | Homology Species | Location | Identity | Homology Identity |
|---|---|---|---|---|
| CDX72487 | Canola | cytosol | 31.5 | 95.19 |
| Bra011543.1-P | Field mustard | cytosol | 77.52 | 87.78 |
| CDY45317 | Canola | cytosol | 75.75 | 86.12 |
| Bra017662.1-P | Field mustard | cytosol | 76.81 | 86.11 |
| AT2G16370.1 | Thale cress | cytosol | 78.94 | 85.93 |
| CDX69070 | Canola | mitochondrion, plastid | 81.59 | 83.82 |
| CDX75443 | Canola | mitochondrion | 81.24 | 80.67 |
| KRH60811 | Soybean | nucleus | 70.27 | 74.91 |
| KRH29421 | Soybean | cytosol | 69.03 | 73.86 |
| KRH24440 | Soybean | cytosol, nucleus | 69.2 | 73.77 |
| VIT_18s0001g12940.t01 | Wine grape | cytosol | 64.96 | 73.11 |
| Solyc01g109830.2.1 | Tomato | cytosol | 67.96 | 72.87 |
| PGSC0003DMT400001937 | Potato | cytosol | 67.43 | 72.3 |
| Zm00001d007318_P001 | Maize | cytosol | 66.73 | 72.08 |
| Os12t0446900-01 | Rice | cytosol | 66.19 | 71.78 |
| Os11t0484400-01 | Rice | cytosol, plasma membrane, plastid | 66.02 | 71.59 |
| KRH51504 | Soybean | nucleus | 70.44 | 70.07 |
| KXG28376 | Sorghum | mitochondrion, plastid | 67.43 | 65.46 |
| Zm00001d030396_P001 | Maize | cytosol | 32.92 | 65.26 |
| Zm00001d049188_P008 | Maize | mitochondrion | 67.08 | 65.12 |
| TraesCS2B01G547000.1 | Wheat | plastid | 66.02 | 64.64 |
| TraesCS2A01G518600.1 | Wheat | mitochondrion, plastid | 65.84 | 64.58 |
| TraesCS2D01G520000.1 | Wheat | plastid | 65.84 | 64.58 |
| Zm00001d050448_P001 | Maize | cytosol | 32.57 | 64.56 |
| VIT_03s0038g04500.t01 | Wine grape | golgi | 69.56 | 62.38 |
| HORVU2Hr1G114640.8 | Barley | cytosol, plastid | 65.49 | 61.06 |
| VIT_18s0075g01010.t01 | Wine grape | cytosol, mitochondrion | 9.38 | 60.92 |
| GSMUA_Achr2P14300_001 | Banana | cytosol | 53.27 | 59.6 |
| AT2G21550.1 | Thale cress | cytosol, plasma membrane, plastid | 49.38 | 56.71 |
| Os11t0615250-00 | Rice | cytosol | 7.79 | 39.64 |
Protein Annotations
| KEGG:00240+2.1.1.45 | KEGG:00670+1.5.1.3 | KEGG:00670+1.5.1.3+2.1.1.45 | KEGG:00670+2.1.1.45 | KEGG:00790+1.5.1.3 | Gene3D:3.30.572.10 |
| Gene3D:3.40.430.10 | MapMan:6.3.1.2 | MapMan:7.5.5 | EntrezGene:829609 | UniProt:A0A178UZ11 | ProteinID:AAA32789.1 |
| ProteinID:AEE86394.1 | EMBL:AK227728 | ArrayExpress:AT4G34570 | EnsemblPlantsGene:AT4G34570 | RefSeq:AT4G34570 | TAIR:AT4G34570 |
| RefSeq:AT4G34570-TAIR-G | EnsemblPlants:AT4G34570.1 | TAIR:AT4G34570.1 | EMBL:BT003159 | ProteinID:CAA18836.1 | ProteinID:CAB80174.1 |
| InterPro:DHFR-TS | InterPro:DHFR-like_dom_sf | InterPro:DHFR_CS | InterPro:DHFR_dom | GO:GO:0003674 | GO:GO:0003824 |
| GO:GO:0004146 | GO:GO:0004799 | GO:GO:0006139 | GO:GO:0006231 | GO:GO:0006545 | GO:GO:0006730 |
| GO:GO:0008150 | GO:GO:0008152 | GO:GO:0008168 | GO:GO:0009058 | GO:GO:0009165 | GO:GO:0009257 |
| GO:GO:0009987 | GO:GO:0016491 | GO:GO:0016740 | GO:GO:0032259 | GO:GO:0046654 | GO:GO:0055114 |
| InterPro:IPR001796 | InterPro:IPR024072 | InterPro:IPR036926 | HAMAP:MF_00008 | RefSeq:NP_001328948.1 | RefSeq:NP_001328950.1 |
| RefSeq:NP_195183.2 | ProteinID:OAO98773.1 | PFAM:PF00186 | PFAM:PF00303 | PIRSF:PIRSF000389 | PO:PO:0000293 |
| PRINTS:PR00108 | ScanProsite:PS00075 | ScanProsite:PS00091 | PFscan:PS51330 | PANTHER:PTHR11548 | PANTHER:PTHR11548:SF7 |
| UniProt:Q05763 | SUPFAM:SSF53597 | SUPFAM:SSF55831 | Symbol:THY-2 | TIGRFAMs:TIGR03284 | InterPro:Thymidate_synth/dCMP_Mease |
| InterPro:Thymidate_synth/dCMP_Mease_sf | InterPro:Thymidylate_synthase | InterPro:Thymidylate_synthase_AS | UniParc:UPI0000196ED8 | SEG:seg | : |
Description
THY-2Bifunctional dihydrofolate reductase-thymidylate synthase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q05763]
Coordinates
chr4:-:16510933..16514372
Molecular Weight (calculated)
63212.1 Da
IEP (calculated)
8.012
GRAVY (calculated)
-0.196
Length
565 amino acids
Sequence
(BLAST)
(BLAST)
001: MRCLQNSAKT LPLAFKSALL PLSQRWFCKF SPKPSSLTNI FKVSISTMAN TLNGNVIMTS KPQSTYQVVV AATKEMGIGK DGKLPWNLPT DLKFFKDLTL
101: STSDSAKKNA VVMGRKTWES IPKKYRPLSG RLNVVLSRSS GFDIANTENV VTCSSIDSAL DLLAAPPFSL SIEKVFVIGG GDILREALNK PSCEAIHITE
201: IDTSIDCDTF IPTVDTSAYQ PWCSSFPICE NGLRFSFTTH VRVKSSSAGE ASDESDGSKV LQVDWKKFSS VLPKMIFDRH EEYLYLNLVK EIISNGNLKD
301: DRTGTGTLSK FGCQMKFNLR RNFPLLTTKR VFWRGVVEEL LWFISGSTNA KVLQEKGIRI WDGNASRAYL DGIGLTEREE GDLGPVYGFQ WRHFGAKYTD
401: MHADYTGQGF DQLLDVINKI KNNPDDRRII MSAWNPSDLK LMALPPCHMF AQFYVANGEL SCQMYQRSAD MGLGVPFNIA SYSLLTCILA HVCDLVPGDF
501: IHVIGDAHVY KNHVRPLQEQ LENPPKPFPV LKINPEKKDI DSFVADDFEL IGYDPHKKID MKMAV
101: STSDSAKKNA VVMGRKTWES IPKKYRPLSG RLNVVLSRSS GFDIANTENV VTCSSIDSAL DLLAAPPFSL SIEKVFVIGG GDILREALNK PSCEAIHITE
201: IDTSIDCDTF IPTVDTSAYQ PWCSSFPICE NGLRFSFTTH VRVKSSSAGE ASDESDGSKV LQVDWKKFSS VLPKMIFDRH EEYLYLNLVK EIISNGNLKD
301: DRTGTGTLSK FGCQMKFNLR RNFPLLTTKR VFWRGVVEEL LWFISGSTNA KVLQEKGIRI WDGNASRAYL DGIGLTEREE GDLGPVYGFQ WRHFGAKYTD
401: MHADYTGQGF DQLLDVINKI KNNPDDRRII MSAWNPSDLK LMALPPCHMF AQFYVANGEL SCQMYQRSAD MGLGVPFNIA SYSLLTCILA HVCDLVPGDF
501: IHVIGDAHVY KNHVRPLQEQ LENPPKPFPV LKINPEKKDI DSFVADDFEL IGYDPHKKID MKMAV
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.