Subcellular Localization
min:
: max
Winner_takes_all: cytosol
Predictor Summary:
Predictor Summary:
- plastid 1
- cytosol 2
- mitochondrion 1
- plasma membrane 1
Predictors | GFP | MS/MS | Papers | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PPI
No PPI Data
Homology
Paralog
locus | Identity | Homology Identity |
---|
Ortholog
locus | Homology Species | Location | Identity | Homology Identity |
---|---|---|---|---|
Zm00001d030396_P001 | Maize | cytosol | 52.39 | 96.14 |
Zm00001d050448_P001 | Maize | cytosol | 52.01 | 95.44 |
Os11t0484400-01 | Rice | cytosol, plasma membrane, plastid | 88.53 | 88.87 |
KXG28376 | Sorghum | mitochondrion, plastid | 95.79 | 86.08 |
Zm00001d049188_P008 | Maize | mitochondrion | 94.84 | 85.22 |
CDX72487 | Canola | cytosol | 28.3 | 79.14 |
CDX89705 | Canola | cytosol | 73.61 | 74.9 |
Bra011543.1-P | Field mustard | cytosol | 71.13 | 74.55 |
VIT_18s0001g12940.t01 | Wine grape | cytosol | 71.13 | 74.1 |
KRH29421 | Soybean | cytosol | 74.57 | 73.86 |
KRH60811 | Soybean | nucleus | 74.76 | 73.77 |
KRH24440 | Soybean | cytosol, nucleus | 74.38 | 73.4 |
AT2G16370.1 | Thale cress | cytosol | 72.28 | 72.83 |
CDY45317 | Canola | cytosol | 68.64 | 72.23 |
Bra017662.1-P | Field mustard | cytosol | 69.6 | 72.22 |
Solyc01g109830.2.1 | Tomato | cytosol | 72.47 | 71.92 |
PGSC0003DMT400001937 | Potato | cytosol | 71.13 | 70.59 |
KRH51504 | Soybean | nucleus | 76.1 | 70.07 |
CDX69070 | Canola | mitochondrion, plastid | 71.89 | 68.36 |
AT4G34570.1 | Thale cress | mitochondrion | 72.08 | 66.73 |
GSMUA_Achr2P14300_001 | Banana | cytosol | 63.48 | 65.74 |
CDX75443 | Canola | mitochondrion | 71.13 | 65.38 |
CDY02264 | Canola | cytosol | 72.28 | 61.16 |
Bra013079.1-P | Field mustard | cytosol | 72.28 | 61.16 |
CDX83194 | Canola | cytosol | 46.46 | 56.78 |
Bra000581.1-P | Field mustard | cytosol | 47.8 | 55.31 |
AT2G21550.1 | Thale cress | cytosol, plasma membrane, plastid | 52.01 | 55.28 |
CDY21464 | Canola | cytosol | 29.25 | 50.33 |
Protein Annotations
KEGG:00240+2.1.1.45 | KEGG:00670+1.5.1.3 | KEGG:00670+1.5.1.3+2.1.1.45 | KEGG:00670+2.1.1.45 | KEGG:00790+1.5.1.3 | Gene3D:3.30.572.10 |
Gene3D:3.40.430.10 | EntrezGene:541707 | MapMan:6.3.1.2 | MapMan:7.5.5 | UniProt:A0A1D6F5H8 | InterPro:DHFR-TS |
InterPro:DHFR-like_dom_sf | InterPro:DHFR_CS | InterPro:DHFR_dom | GO:GO:0003674 | GO:GO:0003824 | GO:GO:0004146 |
GO:GO:0004799 | GO:GO:0006139 | GO:GO:0006231 | GO:GO:0006545 | GO:GO:0006730 | GO:GO:0008150 |
GO:GO:0008152 | GO:GO:0008168 | GO:GO:0009058 | GO:GO:0009165 | GO:GO:0009987 | GO:GO:0016491 |
GO:GO:0016740 | GO:GO:0032259 | GO:GO:0046654 | GO:GO:0055114 | InterPro:IPR001796 | InterPro:IPR024072 |
InterPro:IPR036926 | HAMAP:MF_00008 | ProteinID:ONM26533.1 | ProteinID:ONM26537.1 | ProteinID:ONM26538.1 | ProteinID:ONM26540.1 |
ProteinID:ONM26541.1 | ProteinID:ONM26542.1 | ProteinID:ONM26543.1 | ProteinID:ONM26544.1 | ProteinID:ONM26545.1 | ProteinID:ONM26549.1 |
PFAM:PF00186 | PFAM:PF00303 | PIRSF:PIRSF000389 | PRINTS:PR00108 | ScanProsite:PS00075 | ScanProsite:PS00091 |
PFscan:PS51330 | PANTHER:PTHR11548 | PANTHER:PTHR11548:SF7 | SUPFAM:SSF53597 | SUPFAM:SSF55831 | TIGRFAMs:TIGR03284 |
InterPro:Thymidate_synth/dCMP_Mease | InterPro:Thymidate_synth/dCMP_Mease_sf | InterPro:Thymidylate_synthase | InterPro:Thymidylate_synthase_AS | UniParc:UPI000221AA97 | EnsemblPlantsGene:Zm00001d007318 |
EnsemblPlants:Zm00001d007318_P001 | EnsemblPlants:Zm00001d007318_T001 | SEG:seg | : | : | : |
Description
Bifunctional dihydrofolate reductase-thymidylate synthase Dihydrofolate reductase Thymidylate synthase
Coordinates
chr2:+:228269951..228282169
Molecular Weight (calculated)
59169.1 Da
IEP (calculated)
6.836
GRAVY (calculated)
-0.264
Length
523 amino acids
Sequence
(BLAST)
(BLAST)
001: MAMAAVLANG DSQGRPQRNY QVVVAGTRDM GIGKDGVLPW KLPGDLKFFK ELTLITSDPV KKNAVIMGRK TWESIPVKSR PLPGRLNVIL TRSGSFDFAT
101: VENVVICGSM ESALELLAST PYCLSIEKVF VIGGGQVLRE YLKGPACEAI HLTDIQSSIE CDTFIPPVDF SVFQPWYSSF PVIESNIRHS FVSFVRVRKS
201: VAETHESNGK ESTEVDTKND KFETENFSFL PKMVYDRHEE YQYLNLVEDI IRSGAQKNDR TGTGTLSKFG CQMRFNLRKN FPLLTTKRVF WRGVVEELLW
301: FISGSTNAKV LQEKGIHIWD GNASREYLNS VGLAHREEGD LGPIYGFQWR HFGAEYTDMH ADYTGKGFDQ LMDVIDKIKN DPDDRRIILS AWNPSDLKKM
401: ALPPCHMFAQ FYVENGELSC QMYQRSADMG LGVPFNIASY SLLTYMIAQV CDLSPGDFVH VIGDAHVYRN HVRALEEQIQ KMPKPFPILK INPSKKDIDS
501: FMASDFKLVG YDPHQKIEMK MAV
101: VENVVICGSM ESALELLAST PYCLSIEKVF VIGGGQVLRE YLKGPACEAI HLTDIQSSIE CDTFIPPVDF SVFQPWYSSF PVIESNIRHS FVSFVRVRKS
201: VAETHESNGK ESTEVDTKND KFETENFSFL PKMVYDRHEE YQYLNLVEDI IRSGAQKNDR TGTGTLSKFG CQMRFNLRKN FPLLTTKRVF WRGVVEELLW
301: FISGSTNAKV LQEKGIHIWD GNASREYLNS VGLAHREEGD LGPIYGFQWR HFGAEYTDMH ADYTGKGFDQ LMDVIDKIKN DPDDRRIILS AWNPSDLKKM
401: ALPPCHMFAQ FYVENGELSC QMYQRSADMG LGVPFNIASY SLLTYMIAQV CDLSPGDFVH VIGDAHVYRN HVRALEEQIQ KMPKPFPILK INPSKKDIDS
501: FMASDFKLVG YDPHQKIEMK MAV
001: MRCLQNSAKT LPLAFKSALL PLSQRWFCKF SPKPSSLTNI FKVSISTMAN TLNGNVIMTS KPQSTYQVVV AATKEMGIGK DGKLPWNLPT DLKFFKDLTL
101: STSDSAKKNA VVMGRKTWES IPKKYRPLSG RLNVVLSRSS GFDIANTENV VTCSSIDSAL DLLAAPPFSL SIEKVFVIGG GDILREALNK PSCEAIHITE
201: IDTSIDCDTF IPTVDTSAYQ PWCSSFPICE NGLRFSFTTH VRVKSSSAGE ASDESDGSKV LQVDWKKFSS VLPKMIFDRH EEYLYLNLVK EIISNGNLKD
301: DRTGTGTLSK FGCQMKFNLR RNFPLLTTKR VFWRGVVEEL LWFISGSTNA KVLQEKGIRI WDGNASRAYL DGIGLTEREE GDLGPVYGFQ WRHFGAKYTD
401: MHADYTGQGF DQLLDVINKI KNNPDDRRII MSAWNPSDLK LMALPPCHMF AQFYVANGEL SCQMYQRSAD MGLGVPFNIA SYSLLTCILA HVCDLVPGDF
501: IHVIGDAHVY KNHVRPLQEQ LENPPKPFPV LKINPEKKDI DSFVADDFEL IGYDPHKKID MKMAV
101: STSDSAKKNA VVMGRKTWES IPKKYRPLSG RLNVVLSRSS GFDIANTENV VTCSSIDSAL DLLAAPPFSL SIEKVFVIGG GDILREALNK PSCEAIHITE
201: IDTSIDCDTF IPTVDTSAYQ PWCSSFPICE NGLRFSFTTH VRVKSSSAGE ASDESDGSKV LQVDWKKFSS VLPKMIFDRH EEYLYLNLVK EIISNGNLKD
301: DRTGTGTLSK FGCQMKFNLR RNFPLLTTKR VFWRGVVEEL LWFISGSTNA KVLQEKGIRI WDGNASRAYL DGIGLTEREE GDLGPVYGFQ WRHFGAKYTD
401: MHADYTGQGF DQLLDVINKI KNNPDDRRII MSAWNPSDLK LMALPPCHMF AQFYVANGEL SCQMYQRSAD MGLGVPFNIA SYSLLTCILA HVCDLVPGDF
501: IHVIGDAHVY KNHVRPLQEQ LENPPKPFPV LKINPEKKDI DSFVADDFEL IGYDPHKKID MKMAV
Arabidopsis Description
THY-2Bifunctional dihydrofolate reductase-thymidylate synthase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q05763]
SUBAcon: [mitochondrion]
SUBAcon: [mitochondrion]
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.