Factsheet for PGSC0003DMT400001937

Subcellular Localization

min:

: max

Winner_takes_all: cytosol

Predictor Summary:

nucleus 1
plastid 1
mitochondrion 2
cytosol 3
cytoskeleton 1

Predictors

GFP

MS/MS

Papers

PPI

No PPI Data

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
Solyc01g109830.2.1	Tomato	cytosol	94.88	94.88
CDX72487	Canola	cytosol	29.03	81.82
KRH29421	Soybean	cytosol	77.8	77.65
KRH24440	Soybean	cytosol, nucleus	77.99	77.55
KRH60811	Soybean	nucleus	76.28	75.85
AT2G16370.1	Thale cress	cytosol	74.57	75.72
Bra011543.1-P	Field mustard	cytosol	71.54	75.55
CDX89705	Canola	cytosol	73.43	75.29
Bra017662.1-P	Field mustard	cytosol	71.54	74.8
CDY45317	Canola	cytosol	70.21	74.45
Os11t0484400-01	Rice	cytosol, plasma membrane, plastid	72.68	73.51
Os12t0446900-01	Rice	cytosol	72.49	73.32
Zm00001d007318_P001	Maize	cytosol	70.59	71.13
KRH51504	Soybean	nucleus	76.09	70.6
VIT_18s0075g01010.t01	Wine grape	cytosol, mitochondrion	11.57	70.11
CDX69070	Canola	mitochondrion, plastid	72.11	69.09
AT4G34570.1	Thale cress	mitochondrion	72.3	67.43
CDX75443	Canola	mitochondrion	71.92	66.61
VIT_03s0038g04500.t01	Wine grape	golgi	78.94	66.03
Zm00001d030396_P001	Maize	cytosol	35.1	64.91
TraesCS2A01G518600.1	Wheat	mitochondrion, plastid	70.4	64.41
Zm00001d049188_P008	Maize	mitochondrion	70.97	64.26
TraesCS2D01G520000.1	Wheat	plastid	70.21	64.24
Zm00001d050448_P001	Maize	cytosol	34.72	64.21
TraesCS2B01G547000.1	Wheat	plastid	70.21	64.12
KXG28376	Sorghum	mitochondrion, plastid	70.59	63.92
GSMUA_Achr2P14300_001	Banana	cytosol	60.15	62.77
CDY02264	Canola	cytosol	72.11	61.49
Bra013079.1-P	Field mustard	cytosol	72.11	61.49
HORVU2Hr1G114640.8	Barley	cytosol, plastid	69.64	60.56
Bra000581.1-P	Field mustard	cytosol	48.77	56.86
AT2G21550.1	Thale cress	cytosol, plasma membrane, plastid	52.94	56.71
CDX83194	Canola	cytosol	45.35	55.84
CDY21464	Canola	cytosol	29.41	50.99
Os11t0615250-00	Rice	cytosol	8.16	38.74

Protein Annotations

KEGG:00240+2.1.1.45	KEGG:00670+1.5.1.3	KEGG:00670+1.5.1.3+2.1.1.45	KEGG:00670+2.1.1.45	KEGG:00790+1.5.1.3	EntrezGene:102593228
Gene3D:3.30.572.10	Gene3D:3.40.430.10	MapMan:6.3.1.2	MapMan:7.5.5	InterPro:DHFR-TS	InterPro:DHFR-like_dom_sf
InterPro:DHFR_CS	InterPro:DHFR_dom	GO:GO:0003674	GO:GO:0003824	GO:GO:0004146	GO:GO:0004799
GO:GO:0006139	GO:GO:0006231	GO:GO:0006545	GO:GO:0006730	GO:GO:0008150	GO:GO:0008152
GO:GO:0008168	GO:GO:0009058	GO:GO:0009165	GO:GO:0009987	GO:GO:0016491	GO:GO:0016740
GO:GO:0032259	GO:GO:0046654	GO:GO:0055114	InterPro:IPR001796	InterPro:IPR024072	InterPro:IPR036926
UniProt:M0ZJD1	HAMAP:MF_00008	PFAM:PF00186	PFAM:PF00303	EnsemblPlantsGene:PGSC0003DMG400000736	PGSC:PGSC0003DMG400000736
EnsemblPlants:PGSC0003DMT400001937	PIRSF:PIRSF000389	PRINTS:PR00108	ScanProsite:PS00075	ScanProsite:PS00091	PFscan:PS51330
PANTHER:PTHR11548	PANTHER:PTHR11548:SF7	SUPFAM:SSF53597	SUPFAM:SSF55831	TIGRFAMs:TIGR03284	InterPro:Thymidate_synth/dCMP_Mease
InterPro:Thymidate_synth/dCMP_Mease_sf	InterPro:Thymidylate_synthase	InterPro:Thymidylate_synthase_AS	UniParc:UPI000296C144	RefSeq:XP_006365125.1	RefSeq:XP_015159776.1
SEG:seg	:	:	:	:	:

Description

Bifunctional dihydrofolate reductase-thymidylate synthase [Source:PGSC_GENE;Acc:PGSC0003DMG400000736]

Coordinates

chr1:-:86138599..86145134

Molecular Weight (calculated)

59012.6 Da

IEP (calculated)

6.835

GRAVY (calculated)

-0.226

Length

527 amino acids

Sequence
(BLAST)

001: MASETKTGVS NGNGNAHFTP QRTYQVVVAA TQNMGIGKEG KLPWRLPTDL KFFKGITGTT TDPTKRNAVV MGRKTWESIP IEHRPLPGRL NVVLTRSGSF
101: DIATAENVVI CGSLGSALQL LAASPYCLSI ENVFVIGGGE IFRDSLNADG CDAVHITEIE TDIACDTFTP AIDTSVFRPW YSSFPVIENK IRYSFTTYVR
201: VKNSGVETVN QSNSEIPENG SDSSNIEVKS FSFLPKMVFE KHEEFMYLRL VEEIISNGML KDDRTGTGTL SKFGCQMRYN LRRSFPLLTT KKVFWRGVIE
301: ELLWFISGST SAKVLQEKGI HIWDGNASRD YLDSIGLKDR EEGDLGPVYG FQWRHFGARY IDMHTDYSGQ GFDQLADVIN KVKNNPDDRR IILSAWNPSD
401: LKLMALPPCH MFAQFYVANG ELSCQMYQRS ADMGLGVPFN IASYALLTCM IAHVSGLVPG DFIHVVGDAH VYRNHVRPLQ DQLQKLPRPF PVLKINPQKK
501: DIESFVAADF ELTGYDPHQR IEMKMAI

Best Arabidopsis Sequence Match ( AT2G16370.1 )
(BLAST)

001: MATTTLNDSV TTTLASEPQR TYQVVVAATK EMGIGKDGKL PWNLPTDLKF FKDITLTTSD SSKKNAVVMG RKTWESIPIK YRPLSGRLNV VLTRSGGFDI
101: ANTENVVTCS SVDSALDLLA APPYCLSIER VFVIGGGDIL REALNRPSCD AIHLTEIDTS VDCDTFIPAI DTSVYQPWSS SFPVTENGLR FCFTTFVRVK
201: SSADESSDES NGSQSLQFDG KKFLFLPKMV FDQHEEFLYL NMVEDIISNG NVKNDRTGTG TLSKFGCQMK FNLRRSFPLL TTKRVFWRGV VEELLWFISG
301: STNAKVLQEK GIHIWDGNAS REYLDGIGLT EREEGDLGPV YGFQWRHFGA KYTDMHADYT GQGFDQLVDV IDKIKNNPDD RRIIMSAWNP SDLKLMALPP
401: CHMFAQFYVA EGELSCQMYQ RSADMGLGVP FNIASYSLLT CMLAHVCDLV PGDFIHVLGD AHVYKTHVRP LQEQLLNLPK PFPVMKINPE KKQIDSFVAS
501: DFDLTGYDPH KKIEMKMAV

Arabidopsis Description

THY-1Bifunctional dihydrofolate reductase-thymidylate synthase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q05762]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.