Subcellular Localization
min:
: max
Winner_takes_all: cytosol
Predictor Summary:
Predictor Summary:
- nucleus 1
- cytosol 3
- mitochondrion 1
- plasma membrane 1
Predictors | GFP | MS/MS | Papers | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PPI
No PPI Data
Homology
Paralog
locus | Identity | Homology Identity |
---|
Ortholog
locus | Homology Species | Location | Identity | Homology Identity |
---|---|---|---|---|
CDY36489 | Canola | cytosol | 87.82 | 90.95 |
Bra011164.1-P | Field mustard | cytosol, plasma membrane | 52.44 | 71.56 |
CDY08717 | Canola | cytosol, nucleus, plasma membrane | 92.86 | 70.88 |
AT2G19110.2 | Thale cress | cytosol | 69.75 | 70.82 |
Bra038842.1-P | Field mustard | cytosol | 74.79 | 70.02 |
Bra024107.1-P | Field mustard | plasma membrane | 51.6 | 69.54 |
Bra024103.1-P | Field mustard | peroxisome, plasma membrane, vacuole | 42.02 | 65.44 |
Bra011165.1-P | Field mustard | cytosol | 41.68 | 65.44 |
VIT_11s0103g00370.t01 | Wine grape | plasma membrane | 39.24 | 65.04 |
KRH02816 | Soybean | plasma membrane | 36.05 | 57.35 |
TraesCS7B01G320900.1 | Wheat | plasma membrane | 34.54 | 53.66 |
GSMUA_Achr5P22660_001 | Banana | plasma membrane | 36.81 | 53.61 |
HORVU5Hr1G094430.8 | Barley | endoplasmic reticulum, plasma membrane | 31.18 | 48.5 |
KRH19069 | Soybean | plasma membrane | 43.87 | 47.63 |
TraesCS7A01G420000.1 | Wheat | plasma membrane | 36.89 | 46.75 |
TraesCS7D01G412800.1 | Wheat | plasma membrane | 37.06 | 46.67 |
GSMUA_Achr8P24660_001 | Banana | cytosol | 36.89 | 46.65 |
GSMUA_Achr5P21940_001 | Banana | extracellular, plasma membrane | 36.55 | 46.52 |
TraesCS5B01G388000.1 | Wheat | plasma membrane | 32.27 | 46.32 |
TraesCS5A01G383400.1 | Wheat | plasma membrane | 31.43 | 45.83 |
HORVU7Hr1G097210.4 | Barley | plasma membrane | 36.39 | 45.77 |
TraesCS7D01G412400.1 | Wheat | plasma membrane | 38.4 | 45.56 |
TraesCS7A01G419500.1 | Wheat | plasma membrane | 37.48 | 45.28 |
TraesCS7B01G320100.2 | Wheat | plasma membrane | 38.57 | 44.87 |
HORVU7Hr1G097240.1 | Barley | plasma membrane | 37.98 | 44.8 |
TraesCS5D01G392700.1 | Wheat | plasma membrane | 32.1 | 44.78 |
Os06t0700700-02 | Rice | plasma membrane | 40.0 | 44.61 |
EER90320 | Sorghum | plasma membrane | 38.57 | 42.94 |
Zm00001d014669_P007 | Maize | plasma membrane | 38.82 | 42.04 |
EER96099 | Sorghum | cytosol | 31.26 | 41.56 |
Zm00001d005190_P001 | Maize | plastid | 31.26 | 41.43 |
Solyc07g009130.2.1 | Tomato | plastid | 44.62 | 40.78 |
EER96100 | Sorghum | cytosol | 31.34 | 39.98 |
Zm00001d005189_P001 | Maize | plasma membrane | 31.93 | 39.42 |
Os07t0232900-01 | Rice | cytosol, nucleus, plasma membrane | 32.69 | 38.74 |
Zm00001d019226_P003 | Maize | cytosol | 23.78 | 31.69 |
Bra002374.1-P | Field mustard | plastid | 16.22 | 21.81 |
Bra011750.1-P | Field mustard | plastid | 14.03 | 20.42 |
Bra025102.1-P | Field mustard | cytosol | 16.81 | 20.06 |
Bra039194.1-P | Field mustard | plastid | 12.86 | 19.77 |
Bra027573.1-P | Field mustard | cytosol | 16.64 | 19.76 |
Bra011450.1-P | Field mustard | plastid | 15.55 | 19.68 |
Bra003110.1-P | Field mustard | cytosol | 15.55 | 18.94 |
Bra027641.1-P | Field mustard | mitochondrion | 16.72 | 16.69 |
Protein Annotations
Gene3D:2.70.150.20 | MapMan:24.1.2.1.1 | Gene3D:3.30.70.100 | Gene3D:3.40.1110.10 | Gene3D:3.40.50.1000 | InterPro:ATPase_P-typ_P_site |
InterPro:ATPase_P-typ_TM_dom_sf | InterPro:ATPase_P-typ_cyto_dom_N | InterPro:ATPase_P-typ_transduc_dom_A_sf | EnsemblPlantsGene:Bra024449 | EnsemblPlants:Bra024449.1 | EnsemblPlants:Bra024449.1-P |
ncoils:Coil | GO:GO:0000166 | GO:GO:0003674 | GO:GO:0003824 | GO:GO:0005215 | GO:GO:0005488 |
GO:GO:0005575 | GO:GO:0006810 | GO:GO:0006812 | GO:GO:0008150 | GO:GO:0016020 | GO:GO:0016021 |
GO:GO:0016787 | GO:GO:0019829 | GO:GO:0030001 | GO:GO:0046872 | GO:GO:0099132 | InterPro:HAD-like_sf |
InterPro:HAD_sf | InterPro:HMA_dom | InterPro:HMA_dom_sf | InterPro:IPR006121 | InterPro:IPR023214 | InterPro:IPR023299 |
UniProt:M4E6P5 | InterPro:P-typ_ATPase_IB | PFAM:PF00122 | PFAM:PF00702 | PRINTS:PR00119 | ScanProsite:PS00154 |
PFscan:PS50846 | PANTHER:PTHR43338 | InterPro:P_typ_ATPase | SUPFAM:SSF55008 | SUPFAM:SSF56784 | SUPFAM:SSF81653 |
SUPFAM:SSF81665 | TIGRFAMs:TIGR01494 | TIGRFAMs:TIGR01525 | TMHMM:TMhelix | UniParc:UPI000253EF1C | SEG:seg |
Description
AT2G19110 (E=0.0) HMA4 | HMA4; cadmium ion transmembrane transporter/ cadmium-transporting ATPase/ zinc ion transmembrane transporter
Coordinates
chrA06:-:15828492..15835447
Molecular Weight (calculated)
129721.0 Da
IEP (calculated)
6.769
GRAVY (calculated)
-0.281
Length
1190 amino acids
Sequence
(BLAST)
(BLAST)
0001: MELQNEDKNK EEEKNTKKKW QKSYFDVLGI CCSSEVPLIE NILKSLDGVK EYSVNVPSRT VIVVHDNLLI SPFQIAKALN QAKFEANVKV DGKTNFKNKW
0101: PSPFAPASGI LLLLSFLKFV YPPLRWIAVA AVAAGIYPIL AKAVASIGRK RVDINILVII TVAATLAMQD YMEAAAVVFL FTIAEWLETR ASYKATAVMQ
0201: SLMSLAPQKA IIAETGEEVE VDEVKVNTIV AVKAGETIPI DGIVVDGNCE VDEKTLTGEA YPVPKQRDST VWAGTINLNG YVSVKTTSLA SDCVVAKMAK
0301: LVEEAQSSKT KSQRLIDKCS QYYTPAIILV SGGFAVVPAV MKLHNLNHWF HLALVVLVSA CPCGLILSTP VATFCALTKA ATSGLLIKSA DYLDTLSKIK
0401: ITAFDKTGTI TRGEFIVIEF RSLHSTKPGL LPEESSLSLS SDHSLVDYAK SVNVEPRTEE VEGYQNFPGE GIYGKIDGND IYIGNKRIGS RAKISTVPEI
0501: EVDTNKGGKT VGYIYVGERL AGVFNLSDAC RSGVAQAMKE LKDLGIKTAM LTGDNQDAAM HAQEQLGNAM DVVHGELLPE DKSRIILEFK KEGPTAMVGD
0601: GVNDAPALAT ADIGISMGIS GSALATQTGH IILMSNDIRR IPQAIRLARR ARRKVVENLF ISITLKVGIL VLAFAGHPLI WAAVLADVGT CLLVILNSML
0701: LLRDKDKTKN KKCYRASSTL LNGKKLEGGA EEELDLEAGL LTKSGQCNSG CCGDKKKQEK VKPSSKSSYT HRHSGCCGDK QQQDNVKTIV KESCCGEKNK
0801: IHMASFSSCK KSTHVKKGGS GCCDKKKEKM KETVAKRCCE EKEKNVEMQI LGGQELIDLE KGLAGETCKS RCYGTKEKAA EAAYKVDCNS GSCQENETVK
0901: QRCPEKTCLD IETGDSKLVC YGETEGEVGE QSDLEVKNER ECKSGCCSDE RKQTEEITLA SEEETTEILD CSSSVKQSCH ESTCLEVKEQ FDLKIENEGR
1001: CKSDCCGDEK QTGEITMACE EETDGSDCSS TCCGNKEKVE QSCHEKACLD IEAGVSCDLK LACCGNTEGE VKEKLDFEEG LQIKNQGQCK SDCGLKEEGS
1101: SSLVGKEREI VKVLSQSSNC CTSPTELHVK KKKIEICCKV KTPEAVACES IKCKEREKRH IGKSCCRSYA KEYCSHRHHH HHHHHHVGAV
0101: PSPFAPASGI LLLLSFLKFV YPPLRWIAVA AVAAGIYPIL AKAVASIGRK RVDINILVII TVAATLAMQD YMEAAAVVFL FTIAEWLETR ASYKATAVMQ
0201: SLMSLAPQKA IIAETGEEVE VDEVKVNTIV AVKAGETIPI DGIVVDGNCE VDEKTLTGEA YPVPKQRDST VWAGTINLNG YVSVKTTSLA SDCVVAKMAK
0301: LVEEAQSSKT KSQRLIDKCS QYYTPAIILV SGGFAVVPAV MKLHNLNHWF HLALVVLVSA CPCGLILSTP VATFCALTKA ATSGLLIKSA DYLDTLSKIK
0401: ITAFDKTGTI TRGEFIVIEF RSLHSTKPGL LPEESSLSLS SDHSLVDYAK SVNVEPRTEE VEGYQNFPGE GIYGKIDGND IYIGNKRIGS RAKISTVPEI
0501: EVDTNKGGKT VGYIYVGERL AGVFNLSDAC RSGVAQAMKE LKDLGIKTAM LTGDNQDAAM HAQEQLGNAM DVVHGELLPE DKSRIILEFK KEGPTAMVGD
0601: GVNDAPALAT ADIGISMGIS GSALATQTGH IILMSNDIRR IPQAIRLARR ARRKVVENLF ISITLKVGIL VLAFAGHPLI WAAVLADVGT CLLVILNSML
0701: LLRDKDKTKN KKCYRASSTL LNGKKLEGGA EEELDLEAGL LTKSGQCNSG CCGDKKKQEK VKPSSKSSYT HRHSGCCGDK QQQDNVKTIV KESCCGEKNK
0801: IHMASFSSCK KSTHVKKGGS GCCDKKKEKM KETVAKRCCE EKEKNVEMQI LGGQELIDLE KGLAGETCKS RCYGTKEKAA EAAYKVDCNS GSCQENETVK
0901: QRCPEKTCLD IETGDSKLVC YGETEGEVGE QSDLEVKNER ECKSGCCSDE RKQTEEITLA SEEETTEILD CSSSVKQSCH ESTCLEVKEQ FDLKIENEGR
1001: CKSDCCGDEK QTGEITMACE EETDGSDCSS TCCGNKEKVE QSCHEKACLD IEAGVSCDLK LACCGNTEGE VKEKLDFEEG LQIKNQGQCK SDCGLKEEGS
1101: SSLVGKEREI VKVLSQSSNC CTSPTELHVK KKKIEICCKV KTPEAVACES IKCKEREKRH IGKSCCRSYA KEYCSHRHHH HHHHHHVGAV
0001: MALQNKEEEK KKVKKLQKSY FDVLGICCTS EVPIIENILK SLDGVKEYSV IVPSRTVIVV HDSLLISPFQ IAKALNEARL EANVRVNGET SFKNKWPSPF
0101: AVVSGLLLLL SFLKFVYSPL RWLAVAAVAA GIYPILAKAF ASIKRPRIDI NILVIITVIA TLAMQDFMEA AAVVFLFTIS DWLETRASYK ATSVMQSLMS
0201: LAPQKAIIAE TGEEVEVDEV KVDTVVAVKA GETIPIDGIV VDGNCEVDEK TLTGEAFPVP KQRDSTVWAG TINLNGYICV KTTSLAGDCV VAKMAKLVEE
0301: AQSSKTKSQR LIDKCSQYYT PAIILVSACV AIVPVIMKVH NLKHWFHLAL VVLVSGCPCG LILSTPVATF CALTKAATSG LLIKSADYLD TLSKIKIVAF
0401: DKTGTITRGE FIVIDFKSLS RDINLRSLLY WVSSVESKSS HPMAATIVDY AKSVSVEPRP EEVEDYQNFP GEGIYGKIDG NDIFIGNKKI ASRAGCSTVP
0501: EIEVDTKGGK TVGYVYVGER LAGFFNLSDA CRSGVSQAMA ELKSLGIKTA MLTGDNQAAA MHAQEQLGNV LDVVHGDLLP EDKSRIIQEF KKEGPTAMVG
0601: DGVNDAPALA TADIGISMGI SGSALATQTG NIILMSNDIR RIPQAVKLAR RARRKVVENV CLSIILKAGI LALAFAGHPL IWAAVLVDVG TCLLVIFNSM
0701: LLLREKKKIG NKKCYRASTS KLNGRKLEGD DDYVVDLEAG LLTKSGNGQC KSSCCGDKKN QENVVMMKPS SKTSSDHSHP GCCGDKKEEK VKPLVKDGCC
0801: SEKTRKSEGD MVSLSSCKKS SHVKHDLKMK GGSGCCASKN EKGKEVVAKS CCEKPKQQVE SVGDCKSGHC EKKKQAEDIV VPVQIIGHAL THVEIELQTK
0901: ETCKTSCCDS KEKVKETGLL LSSENTPYLE KGVLIKDEGN CKSGSENMGT VKQSCHEKGC SDEKQTGEIT LASEEETDDQ DCSSGCCVNE GTVKQSFDEK
1001: KHSVLVEKEG LDMETGFCCD AKLVCCGNTE GEVKEQCRLE IKKEEHCKSG CCGEEIQTGE ITLVSEEETE STNCSTGCCV DKEEVTQTCH EKPASLVVSG
1101: LEVKKDEHCE SSHRAVKVET CCKVKIPEAC ASKCRDRAKR HSGKSCCRSY AKELCSHRHH HHHHHHHHHV SA
0101: AVVSGLLLLL SFLKFVYSPL RWLAVAAVAA GIYPILAKAF ASIKRPRIDI NILVIITVIA TLAMQDFMEA AAVVFLFTIS DWLETRASYK ATSVMQSLMS
0201: LAPQKAIIAE TGEEVEVDEV KVDTVVAVKA GETIPIDGIV VDGNCEVDEK TLTGEAFPVP KQRDSTVWAG TINLNGYICV KTTSLAGDCV VAKMAKLVEE
0301: AQSSKTKSQR LIDKCSQYYT PAIILVSACV AIVPVIMKVH NLKHWFHLAL VVLVSGCPCG LILSTPVATF CALTKAATSG LLIKSADYLD TLSKIKIVAF
0401: DKTGTITRGE FIVIDFKSLS RDINLRSLLY WVSSVESKSS HPMAATIVDY AKSVSVEPRP EEVEDYQNFP GEGIYGKIDG NDIFIGNKKI ASRAGCSTVP
0501: EIEVDTKGGK TVGYVYVGER LAGFFNLSDA CRSGVSQAMA ELKSLGIKTA MLTGDNQAAA MHAQEQLGNV LDVVHGDLLP EDKSRIIQEF KKEGPTAMVG
0601: DGVNDAPALA TADIGISMGI SGSALATQTG NIILMSNDIR RIPQAVKLAR RARRKVVENV CLSIILKAGI LALAFAGHPL IWAAVLVDVG TCLLVIFNSM
0701: LLLREKKKIG NKKCYRASTS KLNGRKLEGD DDYVVDLEAG LLTKSGNGQC KSSCCGDKKN QENVVMMKPS SKTSSDHSHP GCCGDKKEEK VKPLVKDGCC
0801: SEKTRKSEGD MVSLSSCKKS SHVKHDLKMK GGSGCCASKN EKGKEVVAKS CCEKPKQQVE SVGDCKSGHC EKKKQAEDIV VPVQIIGHAL THVEIELQTK
0901: ETCKTSCCDS KEKVKETGLL LSSENTPYLE KGVLIKDEGN CKSGSENMGT VKQSCHEKGC SDEKQTGEIT LASEEETDDQ DCSSGCCVNE GTVKQSFDEK
1001: KHSVLVEKEG LDMETGFCCD AKLVCCGNTE GEVKEQCRLE IKKEEHCKSG CCGEEIQTGE ITLVSEEETE STNCSTGCCV DKEEVTQTCH EKPASLVVSG
1101: LEVKKDEHCE SSHRAVKVET CCKVKIPEAC ASKCRDRAKR HSGKSCCRSY AKELCSHRHH HHHHHHHHHV SA
Arabidopsis Description
HMA4Putative cadmium/zinc-transporting ATPase HMA4 [Source:UniProtKB/Swiss-Prot;Acc:O64474]
SUBAcon: [cytosol]
SUBAcon: [cytosol]
Hydropathy Plot
About CropPAL
The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.