Factsheet for PGSC0003DMT400048225

Subcellular Localization

min:

: max

Winner_takes_all: mitochondrion

Predictor Summary:

nucleus 1
mitochondrion 5
cytosol 1
plastid 1

Predictors

GFP

MS/MS

Papers

mitochondrion: 14983062

msms PMID: 14983062 doi

Y Balmer, WH Vensel, CK Tanaka, WJ Hurkman, E Gelhaye, N Rouhier, JP Jacquot, W Manieri, P Schürmann, M Droux, BB Buchanan

Department of Plant and Microbial Biology, University of California, 111 Koshland Hall, Berkeley, CA 94720, USA.

PPI

Inferred distinct locusB in Crop

locusB	locations
PGSC0003DMT400048225	mitochondrion, mitochondrion, mitochondrion

Inferred from Arabidopsis experimental PPI

Ath locusA	locusB	Ath locusB	Paper
AT1G54220.1	PGSC0003DMT400048225	AT1G54220.1	24846799
AT1G54220.1	PGSC0003DMT400048225	AT3G13930.1	24846799
AT3G13930.1	PGSC0003DMT400048225	AT3G13930.1	24846799

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
Solyc07g006790.2.1	Tomato	plastid	96.56	96.38
VIT_09s0002g01800.t01	Wine grape	mitochondrion	69.75	69.37
KRH06095	Soybean	mitochondrion	68.66	69.29
KRH47526	Soybean	mitochondrion	68.48	69.1
VIT_11s0016g01870.t01	Wine grape	mitochondrion	68.48	69.1
AT3G13930.1	Thale cress	mitochondrion	66.12	67.72
Bra027386.1-P	Field mustard	mitochondrion	60.87	67.2
Bra001531.1-P	Field mustard	mitochondrion, plastid	56.34	66.74
AT1G54220.1	Thale cress	mitochondrion	64.86	66.42
CDY55206	Canola	mitochondrion	61.41	66.21
Bra037976.1-P	Field mustard	mitochondrion	64.67	65.99
CDX82504	Canola	plastid	63.95	65.61
HORVU6Hr1G003770.1	Barley	cytosol, mitochondrion	62.86	64.98
CDX97529	Canola	mitochondrion	66.12	64.95
CDY33075	Canola	mitochondrion, plastid	65.22	64.86
EES04754	Sorghum	mitochondrion	63.04	64.56
CDX75740	Canola	mitochondrion, plastid	65.58	64.53
TraesCS6D01G024400.1	Wheat	golgi, mitochondrion	63.22	64.39
CDY24058	Canola	mitochondrion	64.67	64.32
TraesCS6B01G028600.1	Wheat	mitochondrion	61.96	64.29
TraesCS6A01G022600.2	Wheat	golgi	62.14	63.75
Os07t0410100-01	Rice	mitochondrion	61.96	63.22
Os02t0105200-01	Rice	mitochondrion	62.32	62.77
Zm00001d053580_P002	Maize	mitochondrion	62.5	62.61
TraesCS7D01G011600.1	Wheat	golgi, mitochondrion	59.96	61.18
TraesCS4A01G481800.3	Wheat	mitochondrion, unclear	59.6	61.04
TraesCS7A01G014600.4	Wheat	golgi, mitochondrion	59.6	60.81
Os06t0105400-02	Rice	mitochondrion	60.51	60.73
Zm00001d016365_P002	Maize	mitochondrion	63.22	56.56
HORVU7Hr1G001330.9	Barley	plastid	59.06	56.5
GSMUA_Achr10P...	Banana	mitochondrion, vacuole	63.04	54.8
PGSC0003DMT400023831	Potato	plastid	26.81	31.9
PGSC0003DMT400033754	Potato	plastid	26.09	31.3
PGSC0003DMT400071652	Potato	mitochondrion	22.28	26.11
PGSC0003DMT400057449	Potato	mitochondrion	21.74	25.64
PGSC0003DMT400029466	Potato	mitochondrion	22.28	24.36

Protein Annotations

KEGG:00010+2.3.1.12	KEGG:00020+2.3.1.12	KEGG:00620+2.3.1.12	EntrezGene:102579301	InterPro:2-oxoA_DH_lipoyl-BS	InterPro:2-oxoacid_DH_actylTfrase
MapMan:2.2.1.2	Gene3D:2.40.50.100	Gene3D:3.30.559.10	Gene3D:4.10.320.10	InterPro:Biotin_lipoyl	InterPro:CAT-like_dom_sf
InterPro:E3-bd_dom_sf	GO:GO:0003674	GO:GO:0003824	GO:GO:0004742	GO:GO:0005575	GO:GO:0005622
GO:GO:0005623	GO:GO:0005737	GO:GO:0005739	GO:GO:0005759	GO:GO:0006090	GO:GO:0008150
GO:GO:0008152	GO:GO:0009987	GO:GO:0016740	GO:GO:0016746	GO:GO:0045254	InterPro:IPR000089
InterPro:IPR004167	InterPro:IPR023213	InterPro:IPR036625	InterPro:LAT1	UniProt:M1BM43	PFAM:PF00198
PFAM:PF00364	PFAM:PF02817	EnsemblPlantsGene:PGSC0003DMG400018735	PGSC:PGSC0003DMG400018735	EnsemblPlants:PGSC0003DMT400048225	ScanProsite:PS00189
PFscan:PS50968	PFscan:PS51826	InterPro:PSBD	PANTHER:PTHR43178	PANTHER:PTHR43178:SF1	SUPFAM:SSF47005
SUPFAM:SSF51230	SUPFAM:SSF52777	InterPro:Single_hybrid_motif	TIGRFAMs:TIGR01349	UniParc:UPI0002965084	RefSeq:XP_006366183.1
SEG:seg	:	:	:	:	:

Description

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase [Source:PGSC_GENE;Acc:PGSC0003DMG400018735]

Coordinates

chr7:+:2531593..2539576

Molecular Weight (calculated)

59643.1 Da

IEP (calculated)

8.573

GRAVY (calculated)

-0.366

Length

552 amino acids

Sequence
(BLAST)

001: MTYATHVLRH SKKIGSSSNL IRHDSAVLVR WFSNGMRPSM EKGDDILRCQ SGLISGERHN IPKSFNRCYS GSAVSNNSCR TVSPRMSCGN ALRTTIAPCT
101: STGSMSFIRR SSGSQAPSRR GFSSASDLPP HQAIGMPSLS PTMTEGNIAR WLKKEGDKVS PGEVLCEVET DKATVEMECM EEGYLAKILH GDGASSIKVG
201: EVIAVTVEEE DDIAKFKDYQ PSTSDATPSP KAPASPPPPK EEVAEKPVTP SQPKVSKPSA ADRIFASPLA RKIAEDHNIP LTNIKGTGPE GRIVKADIDD
301: YLASRGKDAP AAAPKADTSL DYMDIPVAQI RKVTASRLLL SKQTIPHYYL TVDTCVDKLI ELRSRLNSLQ EASGGKKLSV NDLVIKAAAL ALRKVPQCNS
401: SWTNDYIRQY HNVNINVAVQ TDNGLYVPVV RDADKKGLST ISEEVKNLAQ KAKENSLKPQ DYEGGTFTVS NLGGPFGIKQ FCAIINPPQS AILAVGSAEK
501: RVLPGSSEGQ YKFASMMSVT LSCDHRVIDG AIGAEWLKAF KGYIESPESM LL

Best Arabidopsis Sequence Match ( AT3G13930.1 )
(BLAST)

001: MASRIINHSK KLKHVSALLR RDHAVAVRCF SNSTHPSLVG REDIFKARLN YSSVERISKC GTGNVTMLSG ISTTSTKLSS PMAGPKLFKE FISSQMRSVR
101: GFSSSSDLPP HQEIGMPSLS PTMTEGNIAR WLKKEGDKVA PGEVLCEVET DKATVEMECM EEGFLAKIVK EEGAKEIQVG EVIAITVEDE DDIQKFKDYT
201: PSSDTGPAAP EAKPAPSLPK EEKVEKPASA PEAKISKPSS APSEDRIFAS PLARKLAEDN NVPLSSIKGT GPEGRIVKAD VEDFLASGSK ETTAKPSKQV
301: DSKVPALDYV DIPHTQIRKV TASRLAFSKQ TIPHYYLTVD TCVDKMMGLR SQLNSFQEAS GGKRISVNDL VIKAAALALR KVPQCNSSWT DEYIRQFKNV
401: NINVAVQTEN GLYVPVVKDA DKKGLSTIGE EVRFLAQKAK ENSLKPEDYE GGTFTVSNLG GPFGIKQFCA VINPPQAAIL AIGSAEKRVV PGTGPDQYNV
501: ASYMSVTLSC DHRVIDGAIG AEWLKAFKGY IETPESMLL

Arabidopsis Description

Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q8RWN9]
SUBAcon: [mitochondrion]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.