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Wheat
Subcellular Localization
min:
: max

 
Winner_takes_all: endoplasmic reticulum

Predictor Summary:
  • extracellular 4
  • endoplasmic reticulum 6
  • vacuole 4
  • plasma membrane 5
  • golgi 4
PPI

Inferred distinct locusB in Crop

locusBlocations
TraesCS1A01G173200.3
TraesCS1A01G173400.1
TraesCS1A01G181500.1
TraesCS1A01G204700.1
TraesCS1A01G346800.3
TraesCS1B01G191000.1
TraesCS1B01G191100.2
TraesCS1B01G199300.1
TraesCS1B01G218300.1
TraesCS1B01G360800.1
TraesCS1D01G165400.1
TraesCS1D01G165500.1
TraesCS1D01G184800.1
TraesCS1D01G208000.1
TraesCS1D01G349700.1
TraesCS2A01G019400.2
TraesCS2A01G368500.1
TraesCS2B01G027600.1
TraesCS2B01G317700.1 endoplasmic reticulum
TraesCS2B01G385700.2
TraesCS2B01G576700.1
TraesCS2D01G300200.1 endoplasmic reticulum
TraesCS2D01G365300.2
TraesCS2D01G546900.1
TraesCS3A01G151200.1
TraesCS3A01G278800.1
TraesCS3A01G342900.1 endoplasmic reticulum
TraesCS3A01G528000.1
TraesCS3A01G528100.1
TraesCS3A01G529200.1
TraesCS3B01G178100.1
TraesCS3B01G313000.1
TraesCS3B01G375100.1 endoplasmic reticulum
TraesCS3B01G509000.1
TraesCS3B01G596400.1
TraesCS3B01G596600.1
TraesCS3B01G596800.1
TraesCS3B01G597000.1
TraesCS3B01G597200.1
TraesCS3D01G159100.1
TraesCS3D01G279100.1
TraesCS3D01G336900.2 endoplasmic reticulum
TraesCS3D01G533200.1
TraesCS3D01G533300.1
TraesCS3D01G534500.1
TraesCS4A01G144000.1
TraesCS4A01G339000.1
TraesCS4A01G339100.1
TraesCS4A01G341300.1
TraesCS4A01G384700.2
TraesCS4A01G385300.1
TraesCS4A01G445600.1
TraesCS4A01G463600.1
TraesCS4B01G152900.1
TraesCS4B01G332600.1
TraesCS4B01G388500.1
TraesCS4D01G154700.1
TraesCS4D01G329300.1
TraesCS5A01G128500.2
TraesCS5A01G174100.1
TraesCS5A01G265400.1
TraesCS5A01G287700.1
TraesCS5A01G287800.1
TraesCS5A01G330400.1
TraesCS5A01G495200.1
TraesCS5A01G503700.1
TraesCS5A01G552900.1
TraesCS5B01G171600.1
TraesCS5B01G265100.1
TraesCS5B01G287300.1
TraesCS5B01G330500.1
TraesCS5B01G330600.1
TraesCS5B01G533200.1
TraesCS5B01G548300.1
TraesCS5B01G548400.1
TraesCS5B01G570200.1
TraesCS5B01G570300.1
TraesCS5D01G136100.2
TraesCS5D01G178600.1
TraesCS5D01G273300.1
TraesCS5D01G295700.1
TraesCS5D01G295800.1
TraesCS5D01G336100.1
TraesCS5D01G336200.1
TraesCS5D01G535400.1
TraesCS6A01G235900.1
TraesCS6A01G237600.1
TraesCS6B01G264900.1
TraesCS6B01G266100.1
TraesCS6D01G218900.1
TraesCS6D01G220300.1
TraesCS7A01G042600.1
TraesCS7A01G085700.1
TraesCS7A01G086000.1
TraesCS7A01G136400.1
TraesCS7A01G136500.1
TraesCS7A01G201800.1
TraesCS7A01G300700.1
TraesCS7A01G341800.1
TraesCS7A01G373700.1
TraesCS7B01G037400.1
TraesCS7B01G037600.1
TraesCS7B01G108700.1
TraesCS7B01G241100.1
TraesCS7B01G253300.1
TraesCS7D01G023300.1
TraesCS7D01G038200.1
TraesCS7D01G080400.1
TraesCS7D01G080700.1
TraesCS7D01G136400.1
TraesCS7D01G204900.1
TraesCS7D01G296400.1
TraesCS7D01G337800.1
TraesCS7D01G349400.1
TraesCSU01G066100.1
TraesCSU01G084600.1
TraesCSU01G084800.1
TraesCSU01G124700.1
TraesCSU01G175800.1
TraesCSU01G187900.1
TraesCSU01G201300.1
TraesCSU01G206500.1

Inferred from Arabidopsis experimental PPI

Ath locusAlocusBAth locusBPaper
AT2G30490.1 TraesCS1A01G204700.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS1B01G218300.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS1D01G208000.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS4B01G332600.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS4D01G329300.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS5A01G503700.1 AT1G20330.1 23175744
AT2G30490.1 TraesCS5A01G174100.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS5A01G265400.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS5B01G171600.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS5B01G265100.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS5D01G178600.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS5D01G273300.1 AT1G51570.1 23175744
AT2G30490.1 TraesCS1A01G346800.3 AT1G64090.2 23175744
AT2G30490.1 TraesCS1B01G360800.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS1D01G349700.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3A01G151200.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3A01G278800.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3B01G178100.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3B01G313000.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3D01G159100.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS3D01G279100.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS7A01G341800.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS7B01G241100.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS7D01G337800.1 AT1G64090.2 23175744
AT2G30490.1 TraesCS4A01G144000.1 AT2G03510.1 23175744
AT2G30490.1 TraesCS4B01G152900.1 AT2G03510.1 23175744
AT2G30490.1 TraesCS4D01G154700.1 AT2G03510.1 23175744
AT2G30490.1 TraesCS5A01G330400.1 AT2G20990.3 23175744
AT2G30490.1 TraesCS5B01G330500.1 AT2G20990.3 23175744
AT2G30490.1 TraesCS5B01G330600.1 AT2G20990.3 23175744
AT2G30490.1 TraesCS5D01G336100.1 AT2G20990.3 23175744
AT2G30490.1 TraesCS5D01G336200.1 AT2G20990.3 23175744
AT2G30490.1 TraesCS2B01G317700.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS2D01G300200.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3A01G342900.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3B01G375100.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3D01G336900.2 AT2G30490.1 23175744
AT2G30490.1 TraesCS2B01G317700.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS2D01G300200.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3A01G342900.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3B01G375100.1 AT2G30490.1 23175744
AT2G30490.1 TraesCS3D01G336900.2 AT2G30490.1 23175744
AT2G30490.1 TraesCS2A01G368500.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS2B01G385700.2 AT2G45140.1 23175744
AT2G30490.1 TraesCS2D01G365300.2 AT2G45140.1 23175744
AT2G30490.1 TraesCS6A01G237600.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS6B01G266100.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS6D01G220300.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS7A01G300700.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS7D01G296400.1 AT2G45140.1 23175744
AT2G30490.1 TraesCS1A01G346800.3 AT2G46170.1 23175744
AT2G30490.1 TraesCS1B01G360800.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS1D01G349700.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3A01G151200.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3A01G278800.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3B01G178100.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3B01G313000.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3D01G159100.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS3D01G279100.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS7A01G341800.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS7B01G241100.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS7D01G337800.1 AT2G46170.1 23175744
AT2G30490.1 TraesCS2A01G019400.2 AT3G26830.1 23175744
AT2G30490.1 TraesCS2B01G027600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS2B01G576700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS2D01G546900.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3A01G528000.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3A01G528100.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3A01G529200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G509000.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G596400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G596600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G596800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G597000.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3B01G597200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3D01G533200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3D01G533300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS3D01G534500.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G339000.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G339100.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G341300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G384700.2 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G385300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G445600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4A01G463600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS4B01G388500.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5A01G287700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5A01G287800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5A01G495200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5A01G552900.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G287300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G533200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G548300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G548400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G570200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5B01G570300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5D01G295700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5D01G295800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS5D01G535400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G042600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G085700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G086000.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G136400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G136500.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G201800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7A01G373700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7B01G037400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7B01G037600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7B01G108700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7B01G253300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G023300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G038200.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G080400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G080700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G136400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G204900.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS7D01G349400.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G066100.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G084600.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G084800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G124700.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G175800.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G187900.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G201300.1 AT3G26830.1 23175744
AT2G30490.1 TraesCSU01G206500.1 AT3G26830.1 23175744
AT2G30490.1 TraesCS1A01G173200.3 AT3G48890.1 23175744
AT2G30490.1 TraesCS1B01G191100.2 AT3G48890.1 23175744
AT2G30490.1 TraesCS1D01G165500.1 AT3G48890.1 23175744
AT2G30490.1 TraesCS5A01G128500.2 AT5G22460.1 23175744
AT2G30490.1 TraesCS5D01G136100.2 AT5G22460.1 23175744
AT2G30490.1 TraesCS1A01G346800.3 AT5G41600.1 23175744
AT2G30490.1 TraesCS1B01G360800.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS1D01G349700.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3A01G151200.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3A01G278800.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3B01G178100.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3B01G313000.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3D01G159100.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS3D01G279100.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS7A01G341800.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS7B01G241100.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS7D01G337800.1 AT5G41600.1 23175744
AT2G30490.1 TraesCS1A01G173400.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS1B01G191000.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS1D01G165400.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS6A01G235900.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS6B01G264900.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS6D01G218900.1 AT5G52240.1 23175744
AT2G30490.1 TraesCS1A01G181500.1 AT5G53560.1 23175744
AT2G30490.1 TraesCS1B01G199300.1 AT5G53560.1 23175744
AT2G30490.1 TraesCS1D01G184800.1 AT5G53560.1 23175744
Homology

Paralog

locusIdentityHomology Identity

Ortholog

locusHomology SpeciesLocationIdentityHomology Identity
TraesCS3B01G375100.1 Wheat endoplasmic reticulum, extracellular, plasma membrane 99.01 99.01
TraesCS3A01G342900.1 Wheat endoplasmic reticulum, golgi, plasma membrane 98.81 98.81
HORVU3Hr1G080830.1 Barley endoplasmic reticulum 97.43 97.62
PGSC0003DMT400078288 Potato cytosol 53.16 84.06
KRH72830 Soybean endoplasmic reticulum 83.0 83.0
KRH17200 Soybean endoplasmic reticulum 82.61 82.77
PGSC0003DMT400078290 Potato endoplasmic reticulum, golgi 81.23 81.39
CDX84829 Canola extracellular, golgi, plasma membrane 80.43 80.59
CDY23995 Canola extracellular, golgi, plasma membrane 80.04 80.2
Bra018311.1-P Field mustard extracellular, golgi, plasma membrane 79.84 80.0
Bra022803.1-P Field mustard endoplasmic reticulum, extracellular, plasma membrane 79.84 80.0
CDY10741 Canola extracellular, golgi, plasma membrane 79.84 80.0
CDY02068 Canola extracellular, golgi, plasma membrane 79.45 79.6
AT2G30490.1 Thale cress endoplasmic reticulum, golgi, plasma membrane 79.45 79.6
CDY29670 Canola extracellular, golgi, plasma membrane 79.25 79.41
CDX97826 Canola extracellular, golgi, plasma membrane 79.25 79.41
Bra021637.1-P Field mustard extracellular, golgi, plasma membrane 79.05 79.21
VIT_06s0004g08150.t01 Wine grape endoplasmic reticulum, golgi, plasma membrane 78.85 79.01
TraesCS2D01G300200.1 Wheat endoplasmic reticulum 77.87 77.87
TraesCS3D01G136900.1 Wheat endoplasmic reticulum 75.3 76.05
CDX84830 Canola endoplasmic reticulum, golgi, plasma membrane 75.3 75.75
CDY23996 Canola endoplasmic reticulum, extracellular, plasma membrane 71.94 75.68
Bra021636.1-P Field mustard extracellular, golgi, plasma membrane 75.49 75.64
Bra022802.1-P Field mustard endoplasmic reticulum, golgi, plasma membrane 74.9 75.35
CDY29671 Canola extracellular, golgi, plasma membrane 75.1 75.25
CDX97827 Canola endoplasmic reticulum, golgi, plasma membrane 74.9 75.05
TraesCS7D01G393100.1 Wheat plasma membrane 61.66 58.43
TraesCS2D01G162800.1 Wheat plasma membrane 61.26 58.16
Protein Annotations
Gene3D:1.10.630.10MapMan:9.2.1.2InterPro:Cyt_P450InterPro:Cyt_P450_CSInterPro:Cyt_P450_E_grp-IInterPro:Cyt_P450_sf
GO:GO:0003674GO:GO:0003824GO:GO:0005488GO:GO:0005506GO:GO:0008150GO:GO:0008152
GO:GO:0016705GO:GO:0020037GO:GO:0055114InterPro:IPR036396PFAM:PF00067PRINTS:PR00385
PRINTS:PR00463ScanProsite:PS00086PANTHER:PTHR24298PANTHER:PTHR24298:SF56SUPFAM:SSF48264EnsemblPlantsGene:TraesCS3D01G336900
EnsemblPlants:TraesCS3D01G336900.2SEG:seg::::
Description
No Description!
Coordinates
chr3D:-:448494762..448497131
Molecular Weight (calculated)
58079.9 Da
IEP (calculated)
9.468
GRAVY (calculated)
-0.174
Length
506 amino acids
Sequence
(BLAST)
001: MDFVFVEKLL VGLLAAVVGA IVVSKIRGRK LRLPPGPFPV PIFGNWLQVG DDLNHRNLAA MARKFGEVFL LRMGQRNLVV VSSPPLAREV LHTQGVEFGS
101: RTRNVVFDIF TGEGQDMVFT VYGDHWRKMR RIMTVPFFTN KVVQQYRPGW EAEAAFVVDN VRADPRAATD GVVLRRHLQL MMYNNMYRIM FDRRFESMDD
201: PLFLRLRALN GERSRLAQSF EYNYGDFIPI LRPFLRGYLR LCKEVKETRL KLFKDYFLDE RKKLVSTKAM DNNGGLKCAI DHILEAEQKG EINEDNVLYI
301: IENINVAAIE TTLWSIEWGL AELVNHPEIQ QKLRDEMDAV LGVGHQITEP DTHRLPYLQA VIKETLRLRM AIPLLVPHMN LHDAKLAGYN IPAESKILVN
401: AWFLANNPEQ WKRPDEFRPE RFLEEEKHVE ANGNDFRYLP FGVGRRSCPG IILALPILGI TIGRLVQNFV LSPPPGQDKL DTTEKGGQFS LHILKHSTIV
501: AKPRVF
Best Arabidopsis Sequence Match ( AT2G30490.1 )
(BLAST)
001: MDLLLLEKSL IAVFVAVILA TVISKLRGKK LKLPPGPIPI PIFGNWLQVG DDLNHRNLVD YAKKFGDLFL LRMGQRNLVV VSSPDLTKEV LLTQGVEFGS
101: RTRNVVFDIF TGKGQDMVFT VYGEHWRKMR RIMTVPFFTN KVVQQNREGW EFEAASVVED VKKNPDSATK GIVLRKRLQL MMYNNMFRIM FDRRFESEDD
201: PLFLRLKALN GERSRLAQSF EYNYGDFIPI LRPFLRGYLK ICQDVKDRRI ALFKKYFVDE RKQIASSKPT GSEGLKCAID HILEAEQKGE INEDNVLYIV
301: ENINVAAIET TLWSIEWGIA ELVNHPEIQS KLRNELDTVL GPGVQVTEPD LHKLPYLQAV VKETLRLRMA IPLLVPHMNL HDAKLAGYDI PAESKILVNA
401: WWLANNPNSW KKPEEFRPER FFEEESHVEA NGNDFRYVPF GVGRRSCPGI ILALPILGIT IGRMVQNFEL LPPPGQSKVD TSEKGGQFSL HILNHSIIVM
501: KPRNC
Arabidopsis Description
CYP73A5Cinnamate-4-hydroxylase [Source:UniProtKB/TrEMBL;Acc:B1GV49]
SUBAcon: [endoplasmic reticulum,golgi,plasma membrane]
Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.