CropPAL

Subcellular Localization

min:

: max

Winner_takes_all: cytosol

Predictor Summary:

cytosol 4
mitochondrion 1

Predictors

GFP

MS/MS

Papers

Winner Takes All:	cytosol
Any Predictor:	cytosol
BaCelLo:	cytosol
MultiLoc:	cytosol
PProwler:	mitochondrion
WoLF PSORT:	cytosol
YLoc:	cytosol

PPI

Inferred distinct locusB in Crop

locusB	locations
CDX92643
CDY03441
CDY11021
CDY34291

Inferred from Arabidopsis experimental PPI

Ath locusA	locusB	Ath locusB	Paper
AT4G13930.1	CDX92643	AT4G24560.1	23232097
AT4G13930.1	CDY03441	AT4G24560.1	23232097
AT4G13930.1	CDY11021	AT4G24560.1	23232097
AT4G13930.1	CDY34291	AT4G24560.1	23232097

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
CDY50421	Canola	cytosol	100.0	100.0
CDY47310	Canola	cytosol	98.85	98.85
CDY69223	Canola	cytosol	98.85	91.08
Zm00001d040457_P001	Maize	mitochondrion	20.28	90.72
AT4G13930.1	Thale cress	cytosol	92.86	85.56
PGSC0003DMT400040717	Potato	cytosol	90.32	83.23
Solyc05g053810.2.1	Tomato	nucleus, plastid	90.09	83.01
GSMUA_Achr9P01620_001	Banana	cytosol	83.64	82.88
VIT_05s0029g00310.t01	Wine grape	cytosol	88.94	81.95
PGSC0003DMT400011868	Potato	cytosol	88.25	81.32
Solyc12g098490.1.1	Tomato	extracellular, nucleus, unclear	88.02	81.1
KRH58850	Soybean	cytosol	88.48	80.17
GSMUA_Achr6P06520_001	Banana	cytosol	81.57	79.55
EES08452	Sorghum	cytosol	85.02	78.34
Os11t0455800-01	Rice	plasma membrane	84.79	78.13
TraesCS2A01G493700.1	Wheat	plastid	84.33	77.71
TraesCS2D01G493600.1	Wheat	cytosol	84.33	77.71
TraesCS2B01G521700.1	Wheat	cytosol	84.1	77.49
GSMUA_Achr9P07310_001	Banana	cytosol	72.12	77.28
GSMUA_Achr8P00310_001	Banana	cytosol	42.17	72.62
Zm00001d049234_P001	Maize	plastid	85.02	70.15
KRH42751	Soybean	endoplasmic reticulum, nucleus	90.09	68.36
HORVU2Hr1G110110.2	Barley	mitochondrion, plastid	83.64	65.88
CDX75685	Canola	mitochondrion	58.99	49.52
CDY49684	Canola	mitochondrion	58.76	49.32
CDX69344	Canola	mitochondrion	58.76	49.32
CDY49212	Canola	mitochondrion	57.37	48.92
CDX96315	Canola	mitochondrion	57.6	48.64
CDX90395	Canola	cytosol	39.17	48.57
CDY38837	Canola	cytosol	61.98	47.78
CDX91734	Canola	cytosol	64.29	47.37
CDY41499	Canola	cytosol	62.21	47.29
CDX72795	Canola	mitochondrion	57.14	46.79
CDY41886	Canola	cytosol	63.59	46.78
CDY30643	Canola	cytosol	61.75	46.29
CDY04695	Canola	cytosol	61.52	45.49
CDY39889	Canola	plastid	59.68	44.66
CDY23328	Canola	golgi, plasma membrane	59.68	41.77
CDY53135	Canola	cytosol	11.52	36.76
CDY47659	Canola	cytosol	11.52	36.76
CDX68316	Canola	mitochondrion	57.37	21.28

Protein Annotations

KEGG:00260+2.1.2.1	KEGG:00460+2.1.2.1	KEGG:00630+2.1.2.1	KEGG:00670+2.1.2.1	KEGG:00680+2.1.2.1	Gene3D:3.40.640.10
Gene3D:3.90.1150.10	MapMan:50.2.1	GO:A0A078IK98	UniProt:A0A078IK98	EnsemblPlants:CDY01173	ProteinID:CDY01173
ProteinID:CDY01173.1	ProteinID:CDY50421.1	GO:GO:0003674	GO:GO:0003824	GO:GO:0004372	GO:GO:0005488
GO:GO:0006545	GO:GO:0006730	GO:GO:0008150	GO:GO:0008152	GO:GO:0009058	GO:GO:0009987
GO:GO:0016740	GO:GO:0019264	GO:GO:0030170	GO:GO:0035999	EnsemblPlantsGene:GSBRNA2T00111262001	InterPro:IPR015421
InterPro:IPR015422	HAMAP:MF_00051	PFAM:PF00464	PIRSF:PIRSF000412	ScanProsite:PS00096	PANTHER:PTHR11680
PANTHER:PTHR11680:SF11	MetaCyc:PWY-1622	MetaCyc:PWY-181	MetaCyc:PWY-2161	MetaCyc:PWY-2201	MetaCyc:PWY-3661
MetaCyc:PWY-3661-1	MetaCyc:PWY-3841	MetaCyc:PWY-5497	InterPro:PyrdxlP-dep_Trfase	InterPro:PyrdxlP-dep_Trfase_dom1	InterPro:PyrdxlP-dep_Trfase_major
SUPFAM:SSF53383	InterPro:Ser_HO-MeTrfase	InterPro:Ser_HO-MeTrfase_PLP_BS	UniPathway:UPA00193	UniPathway:UPA00288	UniParc:UPI0004EE1B60

Description

BnaA04g06460DSerine hydroxymethyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A078IK98]

Coordinates

chrLK031924:-:766671..769018

Molecular Weight (calculated)

47475.8 Da

IEP (calculated)

6.845

GRAVY (calculated)

-0.217

Length

434 amino acids

Sequence
(BLAST)

001: MDPVSAWGNT PLVTVDPEIH DLIEKEKRRQ CRGIELIASE NFTSFAVIEA LGSALTNKYS EGMPGNRYYG GNEFIDQIEN LCQSRALEAF RLDSASWGVN
101: VQPYSGSPAN FAAYTALLQP HDRIMGLDLP SGGHLTHGYY TSGGKKISAT SIYFESLPYK VNFTTGYIDY DKLEEKAMDF RPKLLICGGS AYPRDWDYAR
201: LRAVADKVGA LLLCDMAHIS GLVAAQEAAN PFEYCDVVTT TTHKSLRGPR AGGPHNHQIG ALAVALKQAN TPGFKVYAKQ VKANAVALAN YLMGKGYSIV
301: TGGTENHLVL WDLRPLGLTG NKVEKLCDLC NITLNKNAVF GDSSALAPGG VRIGTPAMTS RGLVEKDFEM IGEFLSRSVT LTLNIQKEHG KLLKDFNKGL
401: VNNKEIEELK ADVEKFSASY EMPGFLMSAM KYQD

Best Arabidopsis Sequence Match ( AT4G13930.1 )
(BLAST)

001: MEPVSSWGNT SLVSVDPEIH DLIEKEKRRQ CRGIELIASE NFTSFAVIEA LGSALTNKYS EGIPGNRYYG GNEFIDEIEN LCRSRALEAF HCDPAAWGVN
101: VQPYSGSPAN FAAYTALLQP HDRIMGLDLP SGGHLTHGYY TSGGKKISAT SIYFESLPYK VNFTTGYIDY DKLEEKALDF RPKLLICGGS AYPRDWDYAR
201: FRAIADKVGA LLLCDMAHIS GLVAAQEAAN PFEYCDVVTT TTHKSLRGPR AGMIFYRKGP KPPKKGQPEG AVYDFEDKIN FAVFPALQGG PHNHQIGALA
301: VALKQANTPG FKVYAKQVKA NAVALGNYLM SKGYQIVTNG TENHLVLWDL RPLGLTGNKV EKLCDLCSIT LNKNAVFGDS SALAPGGVRI GAPAMTSRGL
401: VEKDFEQIGE FLSRAVTLTL DIQKTYGKLL KDFNKGLVNN KDLDQLKADV EKFSASYEMP GFLMSEMKYK D

Arabidopsis Description

SHM4Serine hydroxymethyltransferase 4 [Source:UniProtKB/Swiss-Prot;Acc:O23254]
SUBAcon: [cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.