Factsheet for PGSC0003DMT400089434

Subcellular Localization

min:

: max

Winner_takes_all: cytosol

Predictor Summary:

nucleus 1
cytosol 4
endoplasmic reticulum 1
mitochondrion 1

Predictors

GFP

MS/MS

Papers

PPI

Inferred distinct locusB in Crop

locusB	locations
PGSC0003DMT400015077
PGSC0003DMT400050482
PGSC0003DMT400071510
PGSC0003DMT400073246

Inferred from Arabidopsis experimental PPI

Ath locusA	locusB	Ath locusB	Paper
AT4G34640.1	PGSC0003DMT400071510	AT4G19030.1	21798944
AT4G34640.1	PGSC0003DMT400073246	AT4G19030.1	21798944
AT4G34640.1	PGSC0003DMT400015077	AT5G22290.1	21798944
AT4G34640.1	PGSC0003DMT400050482	AT5G22290.1	21798944

Homology

Paralog

locus	Identity	Homology Identity

Ortholog

locus	Homology Species	Location	Identity	Homology Identity
PGSC0003DMT400021134	Potato	cytosol, extracellular, peroxisome	12.3	88.68
Solyc10g079060.1.1	Tomato	cytosol	95.29	85.25
KRH29364	Soybean	endoplasmic reticulum, mitochondrion	69.63	64.41
KRH24387	Soybean	cytosol	69.37	64.16
PGSC0003DMT400008770	Potato	cytosol	67.8	63.02
VIT_03s0038g00450.t01	Wine grape	cytosol	65.97	61.02
AT4G34650.1	Thale cress	cytosol, nucleus, plasma membrane	64.92	60.05
CDX75450	Canola	cytosol	62.3	59.8
Bra011548.1-P	Field mustard	cytosol	62.3	59.8
CDX69075	Canola	cytosol	62.04	59.55
Bra017668.1-P	Field mustard	cytosol	37.7	59.26
CDX76294	Canola	cytosol	62.04	59.25
GSMUA_Achr4P17290_001	Banana	cytosol	45.29	59.04
CDX75451	Canola	cytosol	63.61	58.84
Os03t0805100-01	Rice	cytosol	61.78	58.56
AT4G34640.1	Thale cress	cytosol	62.83	58.54
GSMUA_Achr4P17270_001	Banana	cytosol, extracellular, plastid	17.28	58.41
Bra011549.1-P	Field mustard	cytosol	63.87	58.37
Bra017667.1-P	Field mustard	cytosol	58.64	57.88
EER93257	Sorghum	cytosol	60.47	57.32
CDY17472	Canola	cytosol	63.61	57.04
TraesCS5D01G465000.1	Wheat	cytosol	60.21	56.93
Zm00001d013048_P005	Maize	cytosol	59.69	56.86
CDX69076	Canola	cytosol, plasma membrane, plastid	63.61	56.78
CDX72494	Canola	cytosol	58.64	56.71
TraesCS5B01G464600.1	Wheat	cytosol	59.69	56.44
CDX72493	Canola	cytosol	62.83	56.34
TraesCS5A01G454500.1	Wheat	cytosol	59.42	56.19
CDY45322	Canola	cytosol	59.16	55.53
Os07t0200700-01	Rice	cytosol	58.9	54.88
CDY45323	Canola	cytosol	31.15	54.59
Bra034641.1-P	Field mustard	cytosol	62.57	54.2
Zm00001d034516_P001	Maize	cytosol	59.69	53.65
GSMUA_Achr2P12480_001	Banana	endoplasmic reticulum, golgi, plasma membrane	62.83	49.9
TraesCS5D01G032600.1	Wheat	cytosol	21.99	47.46
HORVU5Hr1G109300.4	Barley	mitochondrion	59.95	44.47

Protein Annotations

KEGG:00100+2.5.1.21	KEGG:00909+2.5.1.21	Gene3D:1.10.600.10	MapMan:9.1.5.1	GO:GO:0003674	GO:GO:0003824
GO:GO:0004310	GO:GO:0005575	GO:GO:0006629	GO:GO:0006696	GO:GO:0008150	GO:GO:0008152
GO:GO:0008610	GO:GO:0009058	GO:GO:0009987	GO:GO:0016020	GO:GO:0016021	GO:GO:0016740
GO:GO:0051996	InterPro:IPR008949	InterPro:Isoprenoid_synthase_dom_sf	UniProt:M1DI57	PFAM:PF00494	EnsemblPlantsGene:PGSC0003DMG400039005
PGSC:PGSC0003DMG400039005	EnsemblPlants:PGSC0003DMT400089434	PANTHER:PTHR11626	SUPFAM:SSF48576	InterPro:Squ/phyt_synthse	InterPro:Squal_synth-like
TIGRFAMs:TIGR01559	InterPro:Trans_IPPS_HH	UniParc:UPI0002948E77	:	:	:

Description

Squalene synthase [Source:PGSC_GENE;Acc:PGSC0003DMG400039005]

Coordinates

chr10:+:58662506..58666045

Molecular Weight (calculated)

44382.8 Da

IEP (calculated)

6.072

GRAVY (calculated)

-0.079

Length

382 amino acids

Sequence
(BLAST)

001: MQEILMHPDE LYPLVKLMLT AKRVEKKTSV WLLQPHWAFC YATLRKVSRS FALVIQQLPS DLRNVVCVYY LVLRALDTVE DDTSLAIEVR VPILRNFYCN
101: FYDPQWHFSC GTKAFKVLMD QFHHVSTAFL ELDTNYQEVI KDITKRMGEG MAKFLCKEVE TIDDYNEYSF YASGLCGLGL SKFFYVSGRE DLAPESISIS
201: MGLFLQKISI IRDYLEDINE VPKCRMFWPR QIWSKYVNKL EDFKYEENSV KAVQCLNEMV TNALLYVEDC LTSMSSLRDP AIFQFCAIPQ IINMGNLSMY
301: YNNVEIFKGV VEMRRGLCAK IIDQTRTMAD VYRAFYDFCC IMESKVDRDD PNATSTLKRL EAILKTCRDS GTLNQRLSSF SS

Best Arabidopsis Sequence Match ( AT4G34650.1 )
(BLAST)

001: MGSLSTILRH PDELYPLLKL KLAITKAQKQ IPLEPHLAFC YSILHKVSKS FSLVIQQLGT ELRNAVCVFY LILRALDTVE DDTSVPVEIK VPILIAFHRH
101: IYDGDWHFSC GTKEYKLLMD QFHHVSAAFL KLEKGYQEAI EDITKRMGAG MAKFICKEVE TIDDYDEYCH YAAGLVGLGL SKIFIASELE ILTPDWKQIS
201: NSTGLFLQKT NIIKDYLEDI NERPKSRMFW PREIWGKYVD KLEDFKNEEK ATKAVQCLNE MVTNALNHVE DCLKSLASLR DPAIFQSCAI PQIVAIGTLA
301: LCYNNVQVFR GVVRLRRGLI AKVIDRTKTM DDVYGAFYDF SCMLQTKVDN NDPNAMKTLN RLETIKKFCK ENGGLHKRKS YVNDETQSKA IFVVMFVLLL
401: AIVVVYLKAN QCK

Arabidopsis Description

SQS2Inactive squalene synthase 2 [Source:UniProtKB/Swiss-Prot;Acc:O65688]
SUBAcon: [plasma membrane,nucleus,cytosol]

Hydropathy Plot

About CropPAL

The Protein Annotated Locations Database (CropPAL) houses large scale proteomic and GFP localization data from published experimental studies in Soybean (Glycine max), Maize (Zea mays), Wheat (Triticum aestivum), Barley (Hordeum vulgare), Rice (Oryza sativa), Field mustard (Brassica rapa), Canola (Brassica napus), Sorghum (Sorghum bicolor), Potato (Solanum tuberosum), Tomato (Solanum lycopersicum), Banana (Musa acuminata) and Wine grape (Vitis vinifera) as well as precomputed predictions for protein subcellular localizations using protein sequences.